Perioperative Mechanical Circulatory Support for Cardiac Assistance in Thoracic Surgery: A Scoping Review Protocol

IF 2.1 Q2 MEDICINE, GENERAL & INTERNAL
Viviana Teresa Agosta, Jacopo D'Andria Ursoleo, Samuele Bugo, Alice Bottussi, Rosario Losiggio, Fabrizio Monaco
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Abstract

Background and Aims

Over the past decades, the number of cardiac patients (e.g., with advanced heart failure or existing cardiovascular comorbidities that expose them to a heightened risk of acute cardiovascular decompensation) requiring noncardiac surgery is rising. For this patient population, potentially curative surgical treatments may be denied due to their prohibitive perioperative risk. Around 30% of patients undergoing general thoracic surgery experience cardiovascular complications of varying severity that may ultimately result in refractory heart failure and/or hemodynamic instability. In both these scenarios, perioperative implantation of temporary mechanical circulatory support (tMCS) may improve patient outcomes by both expanding preoperative surgical eligibility criteria and enabling safer management of unexpected periprocedural complications. This scoping review seeks to summarize the current existing evidence on the role of tMCS for cardiac assistance in thoracic surgery and provide a thorough overview.

Methods

We will perform a scoping review adhering to the Joanna Briggs Institute (JBI) methodology and the extension for Scoping Reviews of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis checklist (PRISMA). We will carry out a comprehensive search of several online databases to identify studies on the perioperative implantation of tMCS in patients undergoing thoracic surgery to provide cardiac assistance either due to their heightened preoperative cardiac risk (pre-emptive tMCS) or for acute cardiac failure due to inherent surgical complications (bail-out tMCS). Standardized forms will be employed to perform data charting and extraction.

Results

Retrieved studies will be presented through a narrative synthesis following initial categorization, supplemented by descriptive statistical analyses of quantitative data if adequate inter-study homogeneity is observed and further complemented by figures and tables.

Conclusion

The planned scoping review aims to assess the safety and feasibility of perioperative implantation of tMCS in patients undergoing thoracic surgery either to mitigate their heightened cardiovascular risk or as a rescue strategy in the event of life-threatening surgical complications. It will identify knowledge gaps, offer direction for future research, and improve clinical practices within the field.

Abstract Image

胸外科围手术期机械循环支持用于心脏辅助:范围界定审查协议
背景和目的 过去几十年来,需要进行非心脏手术的心脏病患者(如晚期心力衰竭或已有心血管合并症,使其急性心血管失代偿的风险增加)人数不断增加。对于这类患者,由于围手术期风险过高,可能会拒绝潜在的治愈性手术治疗。接受普通胸外科手术的患者中约有 30% 会出现不同程度的心血管并发症,最终可能导致难治性心衰和/或血流动力学不稳定。在这两种情况下,围手术期植入临时机械循环支持(tMCS)可通过扩大术前手术资格标准和更安全地处理意外围手术期并发症来改善患者预后。本范围界定综述旨在总结有关临时机械循环支持在胸外科手术中心脏辅助作用的现有证据,并提供全面的概述。 方法 我们将按照乔安娜-布里格斯研究所 (Joanna Briggs Institute, JBI) 的方法和系统综述和荟萃分析首选报告项目清单 (Preferred Reporting Items for Systematic Reviews and Meta-Analysis checklist, PRISMA) 的扩展方法进行范围界定综述。我们将对多个在线数据库进行全面检索,以确定有关在胸外科手术患者围手术期植入 tMCS 以提供心脏辅助的研究,这些患者或因术前心脏风险增加(先发制人的 tMCS),或因固有的手术并发症导致急性心力衰竭(保外 tMCS)。将采用标准化表格进行数据制表和提取。 检索到的研究结果将在初步分类后通过叙述性综述进行介绍,如果发现研究间有足够的同质性,还将辅以定量数据的描述性统计分析,并进一步辅以图表。 结论 本次计划进行的范围界定综述旨在评估胸外科手术患者围术期植入 tMCS 的安全性和可行性,以降低其心血管风险,或在出现危及生命的手术并发症时作为一种抢救策略。它将找出知识差距,为未来研究提供方向,并改进该领域的临床实践。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Health Science Reports
Health Science Reports Medicine-Medicine (all)
CiteScore
1.80
自引率
0.00%
发文量
458
审稿时长
20 weeks
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