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IF 2.4 4区生物学 Q4 CELL BIOLOGY

Cytoskeleton Pub Date : 2024-10-22 DOI:10.1002/cm.21940

引用次数: 0

Abstract

ON THE BACK COVER: DA-Raf inhibits ERK activation, resulting in the suppression of collective cell migration and invasion of KRAS-mutant cancer cells. In human pancreatic carcinoma MIA PaCa-2 cells, phospho-ERK1/2 (magenta) is suppressed by the expression of EGFP-DA-Raf (green). EGFP-DA-Raf is concentrated on the plasma membrane.

Credit: Aoi Matsuda and Takeshi Endo (Chiba University, Japan)

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封底：DA-Raf 可抑制 ERK 激活，从而抑制 KRAS 突变癌细胞的集体迁移和侵袭。在人类胰腺癌 MIA PaCa-2 细胞中，EGFP-DA-Raf（绿色）的表达抑制了磷酸ERK1/2（品红色）。EGFP-DA-Raf集中在质膜上。资料来源：Aoi Matsuda 和 Takeshi Endo（日本千叶大学）

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cytoskeleton CELL BIOLOGY-

CiteScore

5.50

自引率

3.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Cytoskeleton focuses on all aspects of cytoskeletal research in healthy and diseased states, spanning genetic and cell biological observations, biochemical, biophysical and structural studies, mathematical modeling and theory. This includes, but is certainly not limited to, classic polymer systems of eukaryotic cells and their structural sites of attachment on membranes and organelles, as well as the bacterial cytoskeleton, the nucleoskeleton, and uncoventional polymer systems with structural/organizational roles. Cytoskeleton is published in 12 issues annually, and special issues will be dedicated to especially-active or newly-emerging areas of cytoskeletal research.