Scalp Metastasis From Renal Cell Carcinoma: A Rare Case With Rapid Progression.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL
Cureus Pub Date : 2024-10-28 eCollection Date: 2024-10-01 DOI:10.7759/cureus.72546
Mohammed S Alzahrani, Abdulsamad O Alharbi, Abdulaziz Alghamdi, Abdulrahman Mojallid, Mohamed Alghamdi, Abdullrahman Alayyad, Awnallah Alotaibi, Abdulrhman A Alamri, Rehab Fadag, Mohamed Sheta, Abdulrahman S Khalil, Ibrahem F Alassiri, Abdulghani Khogeer, Adel Elatreisy
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Abstract

Renal cell carcinoma (RCC) is a common renal malignancy that frequently metastasizes, though cutaneous metastasis, particularly to the scalp, is rare and generally indicates a poor prognosis. We report a case of scalp metastasis from RCC in a 69-year-old man who presented with unexplained weight loss and painless hematuria. Imaging revealed a 12-cm renal mass with adrenal, pulmonary, and scalp metastases. The patient's condition rapidly deteriorated, and he died one month after the presentation. Hematogenous spread through Batson's plexus might be the primary mechanism of RCC dissemination to the scalp. While targeted therapies have improved the management of metastatic RCC, the prognosis for patients with skin metastases remains poor.

肾细胞癌头皮转移:进展迅速的罕见病例
肾细胞癌(RCC)是一种常见的肾脏恶性肿瘤,经常发生转移,但皮肤转移,尤其是头皮转移并不多见,一般预后较差。我们报告了一例由 RCC 转移至头皮的病例,患者是一名 69 岁的男性,曾出现不明原因的体重减轻和无痛性血尿。影像学检查发现其肾脏肿块达 12 厘米,并伴有肾上腺、肺部和头皮转移。患者病情迅速恶化,在发病一个月后死亡。通过巴特森丛的血源性扩散可能是 RCC 向头皮扩散的主要机制。虽然靶向疗法改善了转移性 RCC 的治疗,但皮肤转移患者的预后仍然很差。
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