A Case Report on Alveolar Rhabdomyosarcoma in an Indigenous Dog.

IF 1.8 3区 农林科学 Q2 VETERINARY SCIENCES
Farjana Akter, Md Zillur Rahman, Mohammad Mahbubur Rahman, Bristy Dhar Nandita, Md Foisal Shikder, Md Piar Rahaman Shihab, Monoar Sayeed Pallab
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Abstract

A 12 years-old, male indigenous dog was presented to Shahedul Alam Qaderi Teaching Veterinary Hospital (SAQTVH) in Chattogram, Bangladesh with a large tumour on its right front leg. The histopathological findings of the tumour were highly suggestive of an alveolar rhabdomyosarcoma (ARMS). The tumour was surgically removed from the dog. While there had been no recurrence for 5 months, the patient died 5 months post-operatively. The cause of the death and presence of metastasis could not be confirmed as follow-up investigations were declined by the owner. A histopathological study showed poorly differentiated neoplastic mononuclear cells forming nests in an alveolar pattern. Despite that the limited resources prevented myogenin staining for diagnostic confirmation, the well-contained, defined appearance of the tumour supports the diagnosis of ARMS. This report highlights the challenges in diagnosing and treating ARMS in indigenous dogs and emphasizes the need for further research and diagnostic markers to improve detection and management.

土著犬肺泡横纹肌肉瘤病例报告
孟加拉国恰特格勒的沙赫杜尔-阿拉姆-卡德里教学兽医院(SAQTVH)收治了一只 12 岁的雄性土狗,它的右前腿上长了一个巨大的肿瘤。肿瘤的组织病理学检查结果高度提示为肺泡横纹肌肉瘤(ARMS)。通过手术将肿瘤从狗身上切除。虽然术后5个月没有复发,但患者在术后5个月死亡。由于狗主人拒绝接受后续调查,因此无法确认死亡原因和是否存在转移。组织病理学研究显示,分化不良的肿瘤性单核细胞在肺泡中形成巢状。尽管资源有限,无法通过肌原蛋白染色进行确诊,但肿瘤外观清晰,支持 ARMS 的诊断。本报告强调了诊断和治疗土狗 ARMS 所面临的挑战,并强调了进一步研究和诊断标记物以改进检测和管理的必要性。
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来源期刊
Veterinary Medicine and Science
Veterinary Medicine and Science Veterinary-General Veterinary
CiteScore
3.00
自引率
0.00%
发文量
296
期刊介绍: Veterinary Medicine and Science is the peer-reviewed journal for rapid dissemination of research in all areas of veterinary medicine and science. The journal aims to serve the research community by providing a vehicle for authors wishing to publish interesting and high quality work in both fundamental and clinical veterinary medicine and science. Veterinary Medicine and Science publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper. We aim to be a truly global forum for high-quality research in veterinary medicine and science, and believe that the best research should be published and made widely accessible as quickly as possible. Veterinary Medicine and Science publishes papers submitted directly to the journal and those referred from a select group of prestigious journals published by Wiley-Blackwell. Veterinary Medicine and Science is a Wiley Open Access journal, one of a new series of peer-reviewed titles publishing quality research with speed and efficiency. For further information visit the Wiley Open Access website.
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