The emerging role of Never-in-Mitosis A - Related Kinases in the endothelium

IF 3.4 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

International Journal of Biochemistry & Cell Biology Pub Date : 2024-10-24 DOI:10.1016/j.biocel.2024.106679

Nektarios Barabutis, Saikat Fakir

引用次数: 0

Abstract

The endothelium forms a monolayer, which functions to ensure tissue homeostasis. Barrier hyperpermeability has been associated with lung, brain and eye disease. An emerging body of evidence reports the involvement of Never-in-Mitosis A - Related Kinases in vascular responses, suggesting their value as potential therapeutic targets in endothelial-dependent disorders.

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内皮细胞中从未蜕变的 A 相关激酶的新作用

内皮形成一个单层，具有确保组织稳态的功能。屏障高渗透性与肺、脑和眼部疾病有关。越来越多的证据表明，与内皮细胞有关的 A 型激酶参与了血管反应，这表明它们作为内皮依赖性疾病的潜在治疗靶点具有潜在价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Biochemistry & Cell Biology 生物-生化与分子生物学

CiteScore

8.10

自引率

0.00%

发文量

124

审稿时长

19 days

期刊介绍： IJBCB publishes original research articles, invited reviews and in-focus articles in all areas of cell and molecular biology and biomedical research. Topics of interest include, but are not limited to: -Mechanistic studies of cells, cell organelles, sub-cellular molecular pathways and metabolism -Novel insights into disease pathogenesis -Nanotechnology with implication to biological and medical processes -Genomics and bioinformatics