Sexual Distress and Quality of Life in Women With Genital Erosive Lichen Planus-A Cross-sectional Study.

IF 2.4 4区 医学 Q2 OBSTETRICS & GYNECOLOGY
Kristin Helene Skullerud, Petter Gjersvik, Malin Eberhard-Gran, Are Hugo Pripp, Erik Qvigstad, Siri Vangen, Anne Lise Ording Helgesen
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引用次数: 0

Abstract

Objective: The study aimed to assess sexual distress and quality of life in women with moderate-to-severe genital erosive lichen planus (GELP).

Materials and methods: Thirty-six women with GELP were recruited at the Oslo University Hospital in Norway. The diagnosis was confirmed by a dermatologist with experience in vulvovaginal disease and based on characteristic clinical changes in the vulva and/or vagina, and biopsy results if available. Clinical severity was measured using the GELP score with a score ≥5 required for inclusion. Sexual distress was measured using the revised Female Sexual Distress Scale (FSDS-R), and quality of life was measured using the Dermatology Life Quality Index (DLQI). Topical steroid treatment was allowed.

Results: The mean FSDS-R score was 22.7 (range 0-45) with 27 women reporting high scores for sexual distress (FSDS-R score >15). The mean DLQI score was 8.8 (range 1-19) with 15 women reporting a moderate impact (DLQI score 6-10), and 12 women reporting a very large impact (DLQI score 11-20) of GELP on their quality of life. No clear correlations were found between disease severity assessed by GELP scores and FSDS-R or DLQI scores. Age was not correlated with FSDS-R or DLQI scores.

Conclusions: These results demonstrate that a substantial number of women with GELP experience sexual distress and a reduced quality of life.

患有生殖器侵蚀性扁平苔藓的女性的性苦恼和生活质量--一项横断面研究。
研究目的研究旨在评估中重度生殖器糜烂性扁平苔癣(GELP)女性患者的性困扰和生活质量:挪威奥斯陆大学医院招募了 36 名 GELP 女性患者。诊断由一名在外阴阴道疾病方面有经验的皮肤科医生根据外阴和/或阴道的特征性临床变化以及活检结果(如有)进行确诊。临床严重程度采用GELP评分法进行测量,得分≥5分方可纳入研究。性困扰采用修订版女性性困扰量表(FSDS-R)进行测量,生活质量采用皮肤科生活质量指数(DLQI)进行测量。允许进行局部类固醇治疗:FSDS-R的平均得分为22.7分(范围为0-45分),其中27名女性的性困扰得分较高(FSDS-R得分>15分)。平均 DLQI 得分为 8.8(范围为 1-19),其中 15 名女性报告 GELP 对其生活质量有中等程度的影响(DLQI 得分为 6-10),12 名女性报告 GELP 对其生活质量有非常大的影响(DLQI 得分为 11-20)。通过 GELP 分数评估的疾病严重程度与 FSDS-R 或 DLQI 分数之间没有明显的相关性。年龄与 FSDS-R 或 DLQI 分数没有相关性:这些结果表明,相当多的 GELP 女性患者都经历过性困扰和生活质量下降。
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来源期刊
Journal of Lower Genital Tract Disease
Journal of Lower Genital Tract Disease OBSTETRICS & GYNECOLOGY-
CiteScore
6.80
自引率
8.10%
发文量
158
审稿时长
6-12 weeks
期刊介绍: The Journal of Lower Genital Tract Disease is the source for the latest science about benign and malignant conditions of the cervix, vagina, vulva, and anus. The Journal publishes peer-reviewed original research original research that addresses prevalence, causes, mechanisms, diagnosis, course, treatment, and prevention of lower genital tract disease. We publish clinical guidelines, position papers, cost-effectiveness analyses, narrative reviews, and systematic reviews, including meta-analyses. We also publish papers about research and reporting methods, opinions about controversial medical issues. Of particular note, we encourage material in any of the above mentioned categories that is related to improving patient care, avoiding medical errors, and comparative effectiveness research. We encourage publication of evidence-based guidelines, diagnostic and therapeutic algorithms, and decision aids. Original research and reviews may be sub-classified according to topic: cervix and HPV, vulva and vagina, perianal and anal, basic science, and education and learning. The scope and readership of the journal extend to several disciplines: gynecology, internal medicine, family practice, dermatology, physical therapy, pathology, sociology, psychology, anthropology, sex therapy, and pharmacology. The Journal of Lower Genital Tract Disease highlights needs for future research, and enhances health care. The Journal of Lower Genital Tract Disease is the official journal of the American Society for Colposcopy and Cervical Pathology, the International Society for the Study of Vulvovaginal Disease, and the International Federation of Cervical Pathology and Colposcopy, and sponsored by the Australian Society for Colposcopy and Cervical Pathology and the Society of Canadian Colposcopists.
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