Invasive Pulmonary Infection of Malassezia Species in a Patient With Ulcerative Colitis: A Case Report.

Abstract

Malassezia species are lipophilic yeasts recognized for causing skin manifestations, such as pityriasis versicolor. In addition, Malassezia can lead to invasive infection, mostly intravascular catheter-associated sepsis-related lipid-containing total parenteral nutrition in neonates and immunocompromised hosts. We experienced a case of invasive pulmonary Malassezia infection in a patient with refractory ulcerative colitis undergoing immunosuppressive treatment without lipid-containing total parenteral nutrition. Computed tomography (CT) images showed multiple lung nodules with CT halo signs. Finally, he underwent a partial right middle lobectomy and was diagnosed with invasive pulmonary malasseziosis through a genetic analysis. Multiple lung nodules on CT images may be found in invasive pulmonary malasseziosis in immunosuppressed patients with a central venous catheter.