Review perspective on advanced nutrachemicals and anterior cruciate ligament rehabilitation.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-24 DOI:10.1515/znc-2024-0169

Dai Haojie, Sohini Mukherjee, Tanima Bhattacharya

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Abstract

Anterior cruciate ligament (ACL) injuries are prevalent among athletes, necessitating surgical intervention followed by comprehensive rehabilitation. Recently, the integration of nutraceuticals - bioactive compounds from food sources - into rehabilitation protocols has shown promise in enhancing recovery outcomes. This review explores the potential benefits of various nutraceuticals, including omega-3 fatty acids, collagen supplements, vitamin D, glucosamine and chondroitin, curcumin, and branched-chain amino acids (BCAAs), in ACL rehabilitation. These nutraceuticals offer anti-inflammatory properties, support tissue repair, and improve joint and muscle health, which are critical during the rehabilitation process. Despite encouraging preclinical findings, there is a need for robust clinical trials to confirm their efficacy and establish optimal dosages and formulations. Personalized nutrition plans and interdisciplinary collaboration among healthcare providers are essential for optimizing patient care. This perspective underscores the potential of advanced nutraceuticals to revolutionize ACL rehabilitation, paving the way for faster and more effective recovery pathways.

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高级营养化学品与前十字韧带康复的综述。

前十字韧带（ACL）损伤在运动员中非常普遍，需要进行手术治疗，然后进行全面康复。最近，将营养保健品--来自食物的生物活性化合物--纳入康复方案显示出了提高康复效果的前景。本综述探讨了各种营养保健品在前交叉韧带康复中的潜在益处，包括欧米伽-3 脂肪酸、胶原蛋白补充剂、维生素 D、葡萄糖胺和软骨素、姜黄素和支链氨基酸 (BCAA)。这些保健食品具有抗炎特性，支持组织修复，改善关节和肌肉健康，这些在康复过程中至关重要。尽管临床前研究结果令人鼓舞，但仍需要进行强有力的临床试验来确认其疗效，并确定最佳剂量和配方。个性化营养计划和医疗服务提供者之间的跨学科合作对于优化患者护理至关重要。这一观点强调了先进营养保健品彻底改变前交叉韧带康复的潜力，为更快、更有效的康复途径铺平了道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.