[Identification of Predictive Biomarkers for Immune Checkpoint Inhibitors by Immunogenomics].

Abstract

The research field of immunogenomics, which elucidates the detail information of immune cells and HLA based on genomic information, is becoming an essential field for understanding the pathology not only in cancer field but also in autoimmune diseases, organ transplantation, and other areas where immune responses are involved. With the comprehensive understanding of T cell receptors, B cell receptors, cancer mutational profiling, we believe that immunogenomics will greatly contribute to personalized medicine by elucidating various pathological and immunological conditions. In this article, we introduce specific examples of immunogenomics in cancer field for better understanding Immunogenomics.