The relationship between contact lens ultraviolet light transmittance and myopia progression: a large-scale retrospective cohort study.

IF 5.1 4区医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

Precision Clinical Medicine Pub Date : 2024-10-11 eCollection Date: 2024-12-01 DOI:10.1093/pcmedi/pbae022

Hiroyuki Okada, Masao Yoshida, Masaki Takeuchi, Eiichi Okada, Nobuhisa Mizuki

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引用次数: 0

Abstract

Background: The prevalence of myopia is increasing dramatically around the world, and many studies have suggested the possibility that ultraviolet (UV) light is effective to prevent the onset and progression of myopia. However, UV is a risk factor for diseases that cause refractive errors such as cataract and pterygium. In this study, we evaluated the relationship between UV exposure and myopia progression.

Methods: The dataset consisted of a total of 337 396 eyes of patients in the 12-to-29-year age range, who were prescribed soft contact lenses (SCL) for refractive error at Okada Eye Clinic in Japan between 2002 and 2011. They were tracked over a five-year period and did not change the type of SCL. In this retrospective cohort study based on medical records, we divided patients into two groups, one prescribed SCL with UV protection (UV-SCL), and another prescribed SCL without UV protection (UV + SCL).

Results: Change in refractive power over five years was measured and results compared. It was -0.413 diopter (D) in the UV-SCL group and -0.462 D in the UV + SCL group. Thus, the progression of myopia was slower in the UV-SCL group. The results were also analyzed separately by gender and degree of myopia at the time of initial prescription, which all showed significant differences (P < 0.001).

Conclusion: Results suggest that UV exposure may advance myopia. Further research is needed to investigate the underlying mechanisms that could explain this.

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隐形眼镜紫外线透射率与近视发展之间的关系：大规模回顾性队列研究。

背景：近视的发病率在全世界急剧上升，许多研究表明，紫外线（UV）可以有效预防近视的发生和发展。然而，紫外线是导致白内障和翼状胬肉等屈光不正疾病的危险因素。在这项研究中，我们评估了紫外线照射与近视发展之间的关系：数据集包括 2002 年至 2011 年期间在日本冈田眼科医院因屈光不正而配戴软性隐形眼镜（SCL）的 12 至 29 岁患者的 337 396 只眼睛。对他们进行了为期五年的跟踪调查，他们没有更换过软性隐形眼镜的类型。在这项以医疗记录为基础的回顾性队列研究中，我们将患者分为两组，一组配戴了具有紫外线防护功能的SCL（UV-SCL），另一组配戴了无紫外线防护功能的SCL（UV + SCL）：我们测量了患者五年来屈光度的变化，并对结果进行了比较。UV-SCL组的屈光度为-0.413屈光度，UV+SCL组的屈光度为-0.462屈光度。因此，UV-SCL 组的近视发展速度较慢。此外，还按性别和初次配镜时的近视度数对结果进行了单独分析，结果均显示出显著差异（P 结论：紫外线-SCL 组的近视度数加深较慢，而紫外线+SCL 组的近视度数加深较快：结果表明，紫外线照射可能会使近视加深。需要进一步研究其潜在机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Precision Clinical Medicine MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

10.80

自引率

0.00%

发文量

审稿时长

5 weeks

期刊介绍： Precision Clinical Medicine (PCM) is an international, peer-reviewed, open access journal that provides timely publication of original research articles, case reports, reviews, editorials, and perspectives across the spectrum of precision medicine. The journal's mission is to deliver new theories, methods, and evidence that enhance disease diagnosis, treatment, prevention, and prognosis, thereby establishing a vital communication platform for clinicians and researchers that has the potential to transform medical practice. PCM encompasses all facets of precision medicine, which involves personalized approaches to diagnosis, treatment, and prevention, tailored to individual patients or patient subgroups based on their unique genetic, phenotypic, or psychosocial profiles. The clinical conditions addressed by the journal include a wide range of areas such as cancer, infectious diseases, inherited diseases, complex diseases, and rare diseases.