Molecular Testing of Environmental Samples as a Potential Source to Estimate Parasite Infection.

IF 2.8 4区 医学 Q2 INFECTIOUS DISEASES
Rojelio Mejia, Barton Slatko, Cristina Almazan, Ruben Cimino, Alejandro Krolewiecki, Natalia Montellano Duran, Jacob Edwin Valera Aspetty, Paola Andrea Vargas, Chiara Cássia Oliveira Amorim, Stefan Michael Geiger, Ricardo Toshio Fujiwara, Juan David Ramirez, Luz Marina Llangarí-Arizo, Irene Guadalupe, Liliana E Villanueva-Lizama, Julio Vladimir Cruz-Chan, María Leticia Ojeda, Eva Mereles Aranda, Sandra Ocampos Benedetti, Maritza Dalí Camones Rivera, Eddyson Montalvo Sabino, Carlos Pineda, Eric J Wetzel, Philip J Cooper
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Abstract

We discuss the potential usefulness of molecular testing of soil, dust, and water samples to detect medically important parasites, and where such testing could be used to supplement stool sampling in humans. A wide variety of parasites including protozoa and helminths, many of which are zoonotic, have an important infection reservoir in the environment. In some cases, this environmental period is essential for further parasite development. We describe the progress in implementing methods for the molecular detection of these parasites in soil across eight collaborating centers in Latin America and represent a variety of potential applications in improving our understanding of parasite epidemiology and mapping, surveillance, and control of these parasites. This methodology offers new opportunities for improving our understanding of a wide variety of parasites of public health importance and novel tools for their control.

将环境样本分子检测作为估计寄生虫感染的潜在来源。
我们讨论了对土壤、灰尘和水样本进行分子检测以检测医学上重要的寄生虫的潜在用途,以及这种检测可用于补充人类粪便采样的情况。包括原生动物和蠕虫在内的多种寄生虫(其中许多是人畜共患寄生虫)在环境中有一个重要的感染库。在某些情况下,这一环境期对于寄生虫的进一步发展至关重要。我们介绍了拉丁美洲八个合作中心在实施土壤中这些寄生虫的分子检测方法方面取得的进展,并介绍了在提高我们对寄生虫流行病学的认识以及对这些寄生虫的绘图、监测和控制方面的各种潜在应用。这种方法为我们更好地了解对公共卫生具有重要意义的各种寄生虫以及控制这些寄生虫的新工具提供了新的机会。
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来源期刊
Tropical Medicine and Infectious Disease
Tropical Medicine and Infectious Disease Medicine-Public Health, Environmental and Occupational Health
CiteScore
3.90
自引率
10.30%
发文量
353
审稿时长
11 weeks
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