Pupillary Peaking & Presence of Dysphotopsias Following Glaucoma Tube Shunt Surgery.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-26 DOI:10.1080/08820538.2024.2421475

Orlando G Gonzalez Martinez, Marko Oydanich, Siri Uppuluri, Rashika Verma, Albert S Khouri

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引用次数: 0

Abstract

Purpose: To describe the presence of pupillary peaking and dysphotopsias in a sample of eyes following glaucoma drainage device (GDD) surgery.

Methods: Cross-sectional analysis of 68 glaucoma patients with GDD, 45 patients with glaucoma and no GDD, and 50 control patients was conducted in a single academic center. Patients with an appropriate diagnosis that met the inclusion criteria were asked to enroll in the study. All patients received an 8-item dysphotopsia questionnaire and were age-matched. Photographs of pupils were taken to assess pupillary peaking. One-way analysis of variance (ANOVA) testing was performed for statistical analysis.

Results: Of the 68 patients with GDD, 25 (36.76%) had pupillary abnormalities with peaking most commonly occurring in the direction of the tube entry superotemporally, and 50 (73.53%) had reported one or more dysphotopsias. In patients reporting one or more dysphotopsias, the rate of lines, crescents, ghost images, and shadows was significantly higher when compared to glaucoma patients without GDD and control patients (p < .01). This corresponded to a lower best-corrected visual acuity in the GDD group compared to the glaucoma and control groups (p < .001).

Conclusions: Over a third of glaucoma patients receiving GDD had pupillary abnormalities, and nearly 3 out of 4 patients with GDD reported one or more dysphotopsias when compared to glaucoma patients without GDD and an age-matched control group. Glaucoma specialists and patients should be aware of these complications when proceeding with GDD surgery.

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青光眼管分流手术后的瞳孔峰值和视力障碍。

目的：描述青光眼引流装置（GDD）手术后眼球样本中是否存在瞳孔峰值和视力障碍：方法：在一个学术中心对 68 名接受 GDD 的青光眼患者、45 名未接受 GDD 的青光眼患者和 50 名对照组患者进行横断面分析。符合纳入标准的确诊患者被要求参加研究。所有患者都接受了一份包含 8 个项目的视力障碍问卷调查，并进行了年龄匹配。瞳孔照片用于评估瞳孔峰值。统计分析采用单因素方差分析（ANOVA）：在 68 名 GDD 患者中，25 人（36.76%）有瞳孔异常，瞳孔峰值最常出现在颞上管入口方向，50 人（73.53%）报告了一次或多次视力障碍。与无 GDD 的青光眼患者和对照组患者相比，报告过一次或多次视力障碍的患者中，出现线条、新月、鬼影和阴影的比例明显更高（P P 结论）：与未接受 GDD 的青光眼患者和年龄匹配的对照组相比，超过三分之一接受 GDD 的青光眼患者存在瞳孔异常，每 4 名 GDD 患者中就有近 3 人出现一种或多种视力障碍。青光眼专家和患者在进行 GDD 手术时应注意这些并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.