Diagnosis and Management of Preterm Prelabor Rupture of Membranes: A Comprehensive Review of Major Guidelines.

IF 4.3 4区 医学 Q1 OBSTETRICS & GYNECOLOGY
Sonia Giouleka, Ioannis Tsakiridis, Garyfallia Emmanouilidou, Eirini Boureka, Ioannis Kalogiannidis, Apostolos Mamopoulos, Apostolos Athanasiadis, Themistoklis Dagklis
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引用次数: 0

Abstract

Importance: Preterm prelabor rupture of membranes (PPROM) represents a significant contributor of maternal and neonatal morbidity complicating a significant proportion of pregnancies worldwide.

Objective: The aim of this review was to summarize and compare the most recently published guidelines on the diagnosis and management of this critical pregnancy complication.

Evidence acquisition: A comparative review of 3 recently updated national guidelines from the American College of Obstetricians and Gynecologists, the Royal College of Obstetricians and Gynaecologists, and the Society of Obstetricians and Gynaecologists of Canada on PPROM was conducted.

Results: There is an overall agreement that the diagnosis of PPROM should be mainly based on sterile speculum examination and patient's history, followed by additional tests in equivocal cases, although the accuracy and contribution of both ultrasound and amniotic proteins tests in the diagnosis remain debatable. Following PPROM confirmation, all guidelines recommend the performance of vaginal and rectal swabs, the evaluation of fetal and maternal status, the administration of antibiotics and corticosteroids, and the immediate induction of labor, if severe complications are identified. Expectant management from viability until late preterm period is universally recommended; nevertheless, there are discrepancies on the optimal timing of delivery. Magnesium sulfate should be administered in case of imminent preterm delivery; however, there is no consensus on the upper gestational age limit. Recommendations on inpatient and outpatient management of PPROM are also inconsistent. Moreover, there is no common guidance on the use of tocolysis or antibiotic regimens. Finally, all medical societies agree that closer surveillance of future pregnancies is required.

Conclusions: PPROM remains the most common identifiable risk factor of preterm delivery, despite constant improvement in prenatal provision of care. Thus, the establishment of consistent international practice protocols for the timely and accurate diagnosis and the optimal management of this complication seems of vital importance and will hopefully lead to significant reduction of the associated adverse outcomes.

早产胎膜早破的诊断与处理:主要指南的全面回顾。
重要性:早产胎膜早破(PPROM)是导致孕产妇和新生儿发病的一个重要因素,在全球相当一部分妊娠中都会出现这种并发症:本综述旨在总结和比较最新发布的关于诊断和处理这一重要妊娠并发症的指南:对美国妇产科医师学会、英国皇家妇产科医师学会和加拿大妇产科医师学会最近更新的 3 个国家关于 PPROM 的指南进行了比较性综述:结果:尽管超声波和羊膜蛋白检测在诊断中的准确性和作用仍有争议,但总体上一致认为,PPROM 的诊断应主要基于无菌窥器检查和患者病史,然后在不确定的病例中进行其他检测。在确诊早产儿窒息后,所有指南都建议进行阴道和直肠拭子检查、评估胎儿和产妇状况、使用抗生素和皮质类固醇,如果发现严重并发症,应立即引产。从胎儿存活到早产晚期的预产期管理是普遍推荐的;然而,在最佳分娩时间方面却存在分歧。在即将早产的情况下,应使用硫酸镁;但对胎龄上限还没有达成共识。关于早产儿住院和门诊管理的建议也不一致。此外,对溶胎剂或抗生素方案的使用也没有统一的指导意见。最后,所有医学协会都认为需要对未来的妊娠进行更密切的监测:结论:尽管产前护理不断改进,但早产儿猝死症仍是最常见的可识别早产风险因素。因此,为及时准确地诊断和优化处理这种并发症而制定一致的国际实践规程似乎至关重要,并有望显著减少相关的不良后果。
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来源期刊
CiteScore
2.70
自引率
3.20%
发文量
245
审稿时长
>12 weeks
期刊介绍: ​Each monthly issue of Obstetrical & Gynecological Survey presents summaries of the most timely and clinically relevant research being published worldwide. These concise, easy-to-read summaries provide expert insight into how to apply the latest research to patient care. The accompanying editorial commentary puts the studies into perspective and supplies authoritative guidance. The result is a valuable, time-saving resource for busy clinicians.
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