Association between the composite dietary antioxidant index and sarcopenia among United States adults: A cross-sectional study.

IF 3.2 3区 医学 Q2 NUTRITION & DIETETICS
Hao Chen, Dongze Wu, Yajin Chen, Ang Shi, Wanda Cai, Xinxin Yang, Xiaodong Chen
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引用次数: 0

Abstract

Background: Diets high in antioxidants are associated with decreased prevalence of sarcopenia. This study aimed to investigate whether the composite dietary antioxidant index (CDAI) and sarcopenia have an underlying relationship.

Methods: We used the data from the National Health and Nutrition Examination Survey 2011-2018. According to dietary antioxidant intake, the CDAI was calculated for each individual. Appendicular skeletal muscle mass index was employed to determine sarcopenia. Multivariate weighted logistic models and restricted cubic spline regression analysis was undertaken to determine the association between CDAI and sarcopenia.

Results: A total of 7012 participants were enrolled in this study, including 473 with sarcopenia (weighted percentage, 5.6%). Compared with the lowest tertile, those in the highest tertile of the CDAI exhibited a greater likelihood of being male, with lower body mass index, higher education level and economic standard, and more chance of being single or separated. In multivariate weighted logistic models, model 3 revealed a noteworthy inverse association between the CDAI and sarcopenia (odds ratio = 0.94; 95% CI, 0.91-0.98; P = 0.003). Compared with the lowest tertile, the highest tertile of CDAI was associated with a 0.57-fold risk of sarcopenia (95% CI, 0.42-0.77; P < 0.001). The inverse association between CDAI and sarcopenia strengthened in the participants with elevated education levels (P for interaction = 0.003).

Conclusion: The CDAI was inversely correlated with the prevalence of sarcopenia. As a comprehensive measurement representing antioxidant status, the CDAI may help manage and prevent sarcopenia.

美国成年人膳食抗氧化剂综合指数与肌肉疏松症之间的关系:一项横断面研究。
背景:抗氧化剂含量高的膳食与肌肉疏松症发病率的降低有关。本研究旨在探讨膳食抗氧化剂综合指数(CDAI)与肌肉疏松症之间是否存在内在联系:我们使用了2011-2018年全国健康与营养调查的数据。根据膳食抗氧化剂摄入量,计算出每个人的 CDAI。骨骼肌质量指数用于确定肌肉疏松症。通过多变量加权逻辑模型和限制性三次样条回归分析,确定CDAI与肌肉疏松症之间的关联:结果:共有 7012 人参与了这项研究,其中 473 人患有肌肉疏松症(加权百分比为 5.6%)。与最低三等分组相比,CDAI最高三等分组的参与者更有可能是男性,体重指数更低,教育水平和经济水平更高,单身或分居的可能性更大。在多变量加权逻辑模型中,模型 3 显示 CDAI 与肌肉疏松症之间存在显著的反向关系(几率比 = 0.94;95% CI,0.91-0.98;P = 0.003)。与最低三分位数相比,CDAI 的最高三分位数与 0.57 倍的肌少症风险相关(95% CI,0.42-0.77;P 结论:CDAI 与肌少症呈反相关:CDAI与肌肉疏松症的发病率成反比。作为一种代表抗氧化状态的综合测量方法,CDAI 可帮助管理和预防肌肉疏松症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.80
自引率
8.80%
发文量
161
审稿时长
6-12 weeks
期刊介绍: The Journal of Parenteral and Enteral Nutrition (JPEN) is the premier scientific journal of nutrition and metabolic support. It publishes original peer-reviewed studies that define the cutting edge of basic and clinical research in the field. It explores the science of optimizing the care of patients receiving enteral or IV therapies. Also included: reviews, techniques, brief reports, case reports, and abstracts.
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