Discrimination and manic symptoms in early adolescence: A prospective cohort study.

IF 4.9 2区 医学 Q1 CLINICAL NEUROLOGY
Journal of affective disorders Pub Date : 2025-01-15 Epub Date: 2024-10-22 DOI:10.1016/j.jad.2024.10.078
Jason M Nagata, Jennifer Wong, Gabriel Zamora, Abubakr A A Al-Shoaibi, Patrick Low, Kyle T Ganson, Alexander Testa, Jinbo He, Jason M Lavender, Fiona C Baker
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引用次数: 0

Abstract

Purpose: This study aims to investigate the prospective associations between four types of perceived discrimination (country of origin, race and ethnicity, sexual orientation, and weight) and the development of manic symptoms in a diverse, nationwide sample of adolescents aged 9-14 years in the U.S.

Methods: We analyzed prospective cohort data from the Adolescent Brain Cognitive Development Study (N = 7466; ages 9-14 years at Year 1 or 2 in 2017-2020; 48.5 % female; 39.4 % racial/ethnic minority). Multiple zero-inflated negative binomial analyses were conducted to examine the associations between Year 1 or 2 discrimination (by country of origin, race and ethnicity, sexual orientation, weight, sum score), and Year 3 manic symptoms (7 Up Mania scale), adjusting for covariates (age, sex, race and ethnicity, household income, parental education, sipping alcohol, puffing tobacco, anxiety symptoms, depressive symptoms, Year 1 manic symptoms, and study site).

Results: After adjusting for covariates, perceived discrimination based on country of origin (incidence rate ratio [IRR] = 1.46; 95 % confidence interval [CI] 1.15-1.86), sexual orientation (IRR = 1.36; 95 % CI 1.21-1.53), race and ethnicity (IRR = 1.28; 95 % CI 1.13-1.46), weight (IRR = 1.21 95 % CI 1.09-1.34), and sum scores (IRR = 1.18 5 % CI 1.12-1.24), were significantly associated with higher manic symptoms.

Conclusion: Perceived discrimination based on country of origin, race and ethnicity, sexual orientation, weight, and sum scores, are prospectively associated with greater manic symptoms in adolescents. These findings underscore the need for targeted interventions to address discrimination and associated psychological impacts. Efforts to reduce discrimination and to support affected adolescents are important components of comprehensive mental health care and public health strategies.

青少年早期的歧视与躁狂症状:前瞻性队列研究。
目的:本研究旨在调查美国全国范围内9-14岁青少年样本中四种感知到的歧视(原籍国、种族和民族、性取向和体重)与躁狂症状发展之间的前瞻性关联:我们分析了青少年大脑认知发展研究(Adolescent Brain Cognitive Development Study)的前瞻性队列数据(N = 7466;2017-2020 年第 1 年或第 2 年时年龄为 9-14 岁;49.1% 为女性;42.1% 为少数种族/族裔)。在调整协变量(年龄、性别、种族/族裔、家庭收入、父母教育程度、饮酒、吸烟、焦虑症状、抑郁症状、第1年躁狂症状和研究地点)后,对第1年或第2年歧视(按原籍国、种族/族裔、性取向、体重、总分)与第3年躁狂症状(7 Up狂躁量表)之间的关联进行了多重零膨胀负二项分析:53)、种族/民族(IRR = 1.28; 95 % CI 1.13-1.46)、体重(IRR = 1.21 95 % CI 1.09-1.34)和总分(IRR = 1.18 5 % CI 1.12-1.24)与较高的躁狂症状显著相关:结论:基于原籍国、种族/民族、性取向、体重和总分的歧视感与青少年躁狂症状的加重有前瞻性关联。这些研究结果表明,有必要采取有针对性的干预措施,以消除歧视和相关的心理影响。努力减少歧视并为受影响的青少年提供支持,是全面心理保健和公共卫生战略的重要组成部分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of affective disorders
Journal of affective disorders 医学-精神病学
CiteScore
10.90
自引率
6.10%
发文量
1319
审稿时长
9.3 weeks
期刊介绍: The Journal of Affective Disorders publishes papers concerned with affective disorders in the widest sense: depression, mania, mood spectrum, emotions and personality, anxiety and stress. It is interdisciplinary and aims to bring together different approaches for a diverse readership. Top quality papers will be accepted dealing with any aspect of affective disorders, including neuroimaging, cognitive neurosciences, genetics, molecular biology, experimental and clinical neurosciences, pharmacology, neuroimmunoendocrinology, intervention and treatment trials.
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