Volumetric Ultrasound Localization Microscopy.

IF 3 2区工程技术 Q1 ACOUSTICS

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2024-10-25 DOI:10.1109/TUFFC.2024.3485556

Louise Denis, Georges Chabouh, Baptiste Heiles, Olivier Couture

{"title":"Volumetric Ultrasound Localization Microscopy.","authors":"Louise Denis, Georges Chabouh, Baptiste Heiles, Olivier Couture","doi":"10.1109/TUFFC.2024.3485556","DOIUrl":null,"url":null,"abstract":"<p><p>Super-resolution ultrasound (SRUS) has evolved significantly with the advent of Ultrasound Localization Microscopy (ULM). This technique enables sub-wavelength resolution imaging using microbubble contrast agents. Initially confined to 2D imaging, ULM has progressed towards volumetric approaches, allowing for comprehensive three-dimensional visualization of microvascular networks. This review explores the technological advancements and challenges associated with volumetric ULM, focusing on key aspects such as transducer design, acquisition speed, data processing algorithms, or integration into clinical practice. We discuss the limitations of traditional 2D ULM, including dependency on precise imaging plane selection and compromised resolution in microvasculature quantification. In contrast, volumetric ULM offers enhanced spatial resolution and allowed motion correction in all direction, promising transformative insights into microvascular pathophysiology. By examining current research and future directions, this review highlights the potential of volumetric ULM to contribute significantly to diagnostic across various medical conditions, including cancers, arteriosclerosis, strokes, diabetes, and neurodegenerative diseases.</p>","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":null,"pages":null},"PeriodicalIF":3.0000,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1109/TUFFC.2024.3485556","RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ACOUSTICS","Score":null,"Total":0}

引用次数: 0

Abstract

Super-resolution ultrasound (SRUS) has evolved significantly with the advent of Ultrasound Localization Microscopy (ULM). This technique enables sub-wavelength resolution imaging using microbubble contrast agents. Initially confined to 2D imaging, ULM has progressed towards volumetric approaches, allowing for comprehensive three-dimensional visualization of microvascular networks. This review explores the technological advancements and challenges associated with volumetric ULM, focusing on key aspects such as transducer design, acquisition speed, data processing algorithms, or integration into clinical practice. We discuss the limitations of traditional 2D ULM, including dependency on precise imaging plane selection and compromised resolution in microvasculature quantification. In contrast, volumetric ULM offers enhanced spatial resolution and allowed motion correction in all direction, promising transformative insights into microvascular pathophysiology. By examining current research and future directions, this review highlights the potential of volumetric ULM to contribute significantly to diagnostic across various medical conditions, including cancers, arteriosclerosis, strokes, diabetes, and neurodegenerative diseases.

查看原文本刊更多论文

容积超声定位显微镜。

随着超声定位显微镜（ULM）的出现，超分辨率超声（SRUS）得到了长足的发展。这项技术利用微气泡造影剂实现了亚波长分辨率成像。ULM 最初仅限于二维成像，现在已发展为容积成像方法，可实现微血管网络的全面三维可视化。本综述探讨了与容积超短波成像相关的技术进步和挑战，重点关注换能器设计、采集速度、数据处理算法或与临床实践的结合等关键方面。我们讨论了传统二维超低功耗成像技术的局限性，包括对精确成像平面选择的依赖性和微血管量化分辨率的影响。相比之下，容积式超短波成像可提供更高的空间分辨率，并允许在所有方向上进行运动校正，有望为微血管病理生理学提供变革性的见解。通过研究当前的研究和未来的发展方向，这篇综述强调了容积超短波成像技术在各种疾病诊断方面的潜力，包括癌症、动脉硬化、中风、糖尿病和神经退行性疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

IEEE transactions on ultrasonics, ferroelectrics, and frequency control 工程技术-工程：电子与电气

CiteScore

7.70

自引率

16.70%

发文量

583

审稿时长

4.5 months

期刊介绍： IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control includes the theory, technology, materials, and applications relating to: (1) the generation, transmission, and detection of ultrasonic waves and related phenomena; (2) medical ultrasound, including hyperthermia, bioeffects, tissue characterization and imaging; (3) ferroelectric, piezoelectric, and piezomagnetic materials, including crystals, polycrystalline solids, films, polymers, and composites; (4) frequency control, timing and time distribution, including crystal oscillators and other means of classical frequency control, and atomic, molecular and laser frequency control standards. Areas of interest range from fundamental studies to the design and/or applications of devices and systems.