L Darbinyan, M Danielyan, V Chavushyan, K Simonyan, M Babakhanyan, L Hambardzumyan, L Manukyan, A Isoyan, K Karapetyan, V Sarkisian, L Hovhannisyan
{"title":"THE PROTECTIVE EFFECTS OF SELENIUM-ENRICHED HYDROPONIC RADISH ON PARACETAMOL-INDUCED LIVER DAMAGE IN RATS.","authors":"L Darbinyan, M Danielyan, V Chavushyan, K Simonyan, M Babakhanyan, L Hambardzumyan, L Manukyan, A Isoyan, K Karapetyan, V Sarkisian, L Hovhannisyan","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Paracetamol-induced liver toxicity in rats is a well-studied model for liver damage. The present study investigates the morphological changes in hepatic blood vessels and the protective effects of hydroponically grown Radish (Raphanus sativus L.) pretreatment in rats with paracetamol-induced liver damage. The results indicate significant alterations in vascular morphology and liver enzyme levels, specifically alanine aminotransferase (ALT) and aspartate aminotransferase (AST), which serve as indicators of hepatotoxicity. The findings suggest that hydroponic Radish may mitigate the adverse effects of paracetamol on liver health, highlighting the importance of dietary components in preventing micronutrient deficiencies and promoting overall health.</p>","PeriodicalId":12610,"journal":{"name":"Georgian medical news","volume":" 352-353","pages":"168-172"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Georgian medical news","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Paracetamol-induced liver toxicity in rats is a well-studied model for liver damage. The present study investigates the morphological changes in hepatic blood vessels and the protective effects of hydroponically grown Radish (Raphanus sativus L.) pretreatment in rats with paracetamol-induced liver damage. The results indicate significant alterations in vascular morphology and liver enzyme levels, specifically alanine aminotransferase (ALT) and aspartate aminotransferase (AST), which serve as indicators of hepatotoxicity. The findings suggest that hydroponic Radish may mitigate the adverse effects of paracetamol on liver health, highlighting the importance of dietary components in preventing micronutrient deficiencies and promoting overall health.
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