Effects of the Strength, Assistance in walking, Rise from a chair, Climb stairs, and Falls score on postoperative clinical outcomes following colorectal cancer surgery: a retrospective study.

IF 3.6 3区 医学 Q2 NUTRITION & DIETETICS
Young Jae Kim, Sung Uk Bae, Kyeong Eui Kim, Woon Kyung Jeong, Seong Kyu Baek
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引用次数: 0

Abstract

Background/objectives: Sarcopenia has known negative effects on clinical and oncological outcomes in patients with colorectal cancer (CRC). The use of the Strength, Assistance in walking, Rise from a chair, Climb stairs, and Falls (SARC-F) questionnaire to determine the effects of sarcopenia on postoperative complications of CRC has not been reported to date. Therefore, this study aimed to investigate the relationship of SARC-F score with clinicopathologic outcomes after CRC surgery.

Subjects/methods: We retrospectively included 285 patients who completed SARC-F questionnaires before CRC surgery between July 2019 and March 2022. Patients with an SARC-F score ≥4 (total score: 10) were classified in the high SARC-F group.

Results: Overall, 34 (11.9%) patients had high SARC-F scores. These patients were older (76.9 ± 8.5 vs. 64.5 ± 11.4 years, p < 0.001) and had a higher preoperative CRP (2.5 ± 3.9 vs. 0.8 ± 1.6 mg/L, p = 0.019), lower body mass index (21.7 ± 3.4 vs. 24.0 ± 3.8 kg/m2, p = 0.001), and higher pan-immune-inflammation value (632.3 ± 615.5 vs. 388.9 ± 413.8, p = 0.031). More postoperative complications were noted in the high SARC-F group than in the low SARC-F group (58.8% vs. 35.6%, p = 0.009). High SARC-F scores were significantly associated with higher nodal stage, higher number of harvested lymph nodes, and larger tumor size. Univariate and multivariate analyses revealed high SARC-F score and operation time as independent risk factors associated with postoperative complications (odds ratio, 2.212/1.922; 95% confidence interval, 1.021-4.792/1.163-3.175; p = 0.044/0.011, respectively).

Conclusions: Preoperative SARC-F score was an independent risk factor associated with postoperative complications following colorectal cancer surgery.

力量、行走协助、从椅子上站起、爬楼梯和跌倒评分对结直肠癌术后临床效果的影响:一项回顾性研究。
背景/目的:众所周知,肌肉疏松症对结直肠癌(CRC)患者的临床和肿瘤预后有负面影响。使用力量、行走协助、从椅子上站起、爬楼梯和跌倒(SARC-F)问卷来确定肌肉疏松症对 CRC 术后并发症的影响,迄今尚未见报道。因此,本研究旨在调查 SARC-F 评分与 CRC 术后临床病理结果的关系:我们回顾性纳入了2019年7月至2022年3月期间在CRC手术前填写SARC-F问卷的285例患者。SARC-F得分≥4分(总分:10分)的患者被归入高SARC-F组:总体而言,34 名(11.9%)患者的 SARC-F 评分较高。这些患者年龄较大(76.9 ± 8.5 岁 vs. 64.5 ± 11.4 岁,P 2,P = 0.001),泛免疫炎症值较高(632.3 ± 615.5 vs. 388.9 ± 413.8,P = 0.031)。与低 SARC-F 组相比,高 SARC-F 组的术后并发症更多(58.8% 对 35.6%,p = 0.009)。高 SARC-F 评分与较高的结节分期、较多的摘取淋巴结数量和较大的肿瘤体积有明显相关性。单变量和多变量分析显示,高SARC-F评分和手术时间是与术后并发症相关的独立风险因素(几率比分别为2.212/1.922;95%置信区间分别为1.021-4.792/1.163-3.175;P = 0.044/0.011):结论:术前SARC-F评分是与结直肠癌手术后并发症相关的独立风险因素。
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来源期刊
CiteScore
10.60
自引率
2.10%
发文量
189
审稿时长
3-6 weeks
期刊介绍: The European Journal of Clinical Nutrition (EJCN) is an international, peer-reviewed journal covering all aspects of human and clinical nutrition. The journal welcomes original research, reviews, case reports and brief communications based on clinical, metabolic and epidemiological studies that describe methodologies, mechanisms, associations and benefits of nutritional interventions for clinical disease and health promotion. Topics of interest include but are not limited to: Nutrition and Health (including climate and ecological aspects) Metabolism & Metabolomics Genomics and personalized strategies in nutrition Nutrition during the early life cycle Health issues and nutrition in the elderly Phenotyping in clinical nutrition Nutrition in acute and chronic diseases The double burden of ''malnutrition'': Under-nutrition and Obesity Prevention of Non Communicable Diseases (NCD)
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