Drug induced sleep endoscopy and simultaneous polysomnography to predict the effectiveness of mandibular advancement device in obstructive sleep apnea treatment.

IF 1.9 3区医学 Q2 OTORHINOLARYNGOLOGY

European Archives of Oto-Rhino-Laryngology Pub Date : 2024-12-01 Epub Date: 2024-10-23 DOI:10.1007/s00405-024-09017-w

Ottavio Piccin, Irene Pelligra, Giulio Alessandri Bonetti, Anna Bonsembiante

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引用次数: 0

Abstract

Purposes: To evaluate whether mandibular advancement device therapy is recommended in patients affected by obstructive sleep apnea.

Methods: In order to predict oral appliances therapy response, drug induced sleep endoscopy with cardio-respiratory polygraphy and mandibular advancement device simulator was carried out. Patients in which upper airway obstruction was resolved on all levels and AHI was normalized (< 5/h), were referred for oral appliance therapy. At 5 months follow up, a cardio-respiratory polygraphy with MAD was performed.

Results: 36 patients who have evidence of resolution of UA collapse and AHI below 5 events per hour, were referred for MAD therapy. At follow up, the mean AHI decreased from 29.1 ± 13.1 to 3.3/h ± 1.9 (p < 0.001). All the patients were responders.

Conclusion: Combining the evaluation of drug induced sleep endoscopy and cardio-respiratory polygraphy data simultaneously during mandibular protrusion, has the potential to be a useful tool for prediction of MAD therapy response.

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通过药物诱导睡眠内窥镜检查和同步多导睡眠监测来预测下颌前突矫正器在阻塞性睡眠呼吸暂停治疗中的效果。

目的评估是否建议对阻塞性睡眠呼吸暂停患者进行下颌前突矫正器治疗：方法：为了预测口腔矫治器治疗的反应，进行了药物诱导睡眠内窥镜检查，并使用心肺聚光仪和下颌前突矫正器模拟器。患者的上气道阻塞在所有层面上均得到缓解，AHI 恢复正常（结果：36 名患者的上气道阻塞症状得到缓解，AHI 恢复正常）：36 名有证据表明上气道塌陷得到缓解且 AHI 低于每小时 5 次的患者被转诊接受 MAD 治疗。在随访中，平均 AHI 从 29.1 ± 13.1 降至 3.3/h ± 1.9（p 结论：在随访中，平均 AHI 从 29.1 ± 13.1 降至 3.3/h ± 1.9：在下颌前突期间同时评估药物诱导睡眠内窥镜和心肺功能测谎仪数据，有望成为预测 MAD 治疗反应的有用工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.