Clinical Applications of Micro/Nanobubble Technology in Neurological Diseases.

IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY
Parth B Patel, Sun Latt, Karan Ravi, Mehdi Razavi
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引用次数: 0

Abstract

Nanomedicine, leveraging the unique properties of nanoparticles, has revolutionized the diagnosis and treatment of neurological diseases. Among various nanotechnological advancements, ultrasound-mediated drug delivery using micro- and nanobubbles offers promising solutions to overcome the blood-brain barrier (BBB), enhancing the precision and efficacy of therapeutic interventions. This review explores the principles, current clinical applications, challenges, and future directions of ultrasound-mediated drug delivery systems in treating stroke, brain tumors, neurodegenerative diseases, and neuroinflammatory disorders. Additionally, ongoing clinical trials and potential advancements in this field are discussed, providing a comprehensive overview of the impact of nanomedicine on neurological diseases.

微/纳米气泡技术在神经系统疾病中的临床应用。
纳米医学利用纳米粒子的独特特性,彻底改变了神经疾病的诊断和治疗。在各种纳米技术进展中,使用微气泡和纳米气泡的超声介导给药技术为克服血脑屏障(BBB)、提高治疗干预的精确性和有效性提供了前景广阔的解决方案。本综述探讨了超声介导给药系统治疗中风、脑肿瘤、神经退行性疾病和神经炎症性疾病的原理、当前临床应用、挑战和未来发展方向。此外,还讨论了该领域正在进行的临床试验和潜在的进展,全面概述了纳米医学对神经系统疾病的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomimetics
Biomimetics Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
3.50
自引率
11.10%
发文量
189
审稿时长
11 weeks
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