The essential role of combined calcium and vitamin D supplementation in the osteoporosis scenario in italy: Expert opinion paper

IF 3.1 3区医学 Q2 ENDOCRINOLOGY & METABOLISM

Archives of Osteoporosis Pub Date : 2024-10-22 DOI:10.1007/s11657-024-01451-x

Stefano Carugo, Fabio Vescini, Andrea Giusti, Giulia Letizia Mauro, Laura Tafaro, Francescaromana Festuccia, Lucia Muraca, Paolo Menè, Maurizio Rossini

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引用次数: 0

Abstract

Summary

An Italian multidisciplinary working group discussed the current Italian scenario of osteoporosis management during a meeting and highlighted the essential role of calcium and vitamin D supplementation in the prevention of fragility fractures.

Purpose

This paper aims to review and discuss data on calcium and vitamin D requirements and the role of combined calcium and vitamin D supplementation in the treatment of patients with osteoporosis.

Methods

The discussion of the experts covered literature data on calcium and vitamin D supplementation, gaps in the diagnosis and treatment of osteoporosis, and the role of the primary care physician in identifying and treating patients with osteoporosis. Articles for consideration were identified through PubMed searches using different combinations of pertinent keywords.

Results

The discussion highlighted that insufficient calcium or vitamin D intake increases the risk of fragility fractures. The experts also drew attention to the essential role of calcium and vitamin D supplementation in achieving an anti-fracture effect and supporting the efficacy of anti-osteoporotic agents without increasing nephrolithiasis and cardiovascular risks. In addition, the discussion underlined the role of the primary care physician in the initial clinical approach to patients with osteoporosis.

Conclusions

The experts believe that efficient treatment for patients with osteoporosis should include calcium and vitamin D supplementation to achieve adequate levels that are able to inhibit the parathyroid hormone and bone resorption.

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在意大利骨质疏松症患者中联合补充钙和维生素 D 的重要作用：专家意见书。

一个意大利多学科工作组在一次会议上讨论了意大利目前的骨质疏松症治疗情况，并强调了钙和维生素 D 补充剂在预防脆性骨折中的重要作用。目的：本文旨在回顾和讨论有关钙和维生素 D 需求量的数据，以及钙和维生素 D 联合补充剂在骨质疏松症患者治疗中的作用：专家们的讨论涉及钙和维生素 D 补充的文献数据、骨质疏松症诊断和治疗方面的差距以及初级保健医生在识别和治疗骨质疏松症患者中的作用。通过使用不同的相关关键词组合在 PubMed 上进行搜索，确定了供审议的文章：讨论强调，钙或维生素 D 摄入不足会增加脆性骨折的风险。专家们还提请注意，钙和维生素 D 补充剂在实现抗骨折效果和支持抗骨质疏松药物疗效方面发挥着重要作用，同时不会增加肾炎和心血管风险。此外，讨论还强调了初级保健医生在骨质疏松症患者初期临床治疗中的作用：专家们认为，骨质疏松症患者的有效治疗应包括补充钙和维生素 D，以达到能够抑制甲状旁腺激素和骨吸收的适当水平。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of Osteoporosis ENDOCRINOLOGY & METABOLISMORTHOPEDICS -ORTHOPEDICS

CiteScore

5.50

自引率

10.00%

发文量

133

期刊介绍： Archives of Osteoporosis is an international multidisciplinary journal which is a joint initiative of the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA. The journal will highlight the specificities of different regions around the world concerning epidemiology, reference values for bone density and bone metabolism, as well as clinical aspects of osteoporosis and other bone diseases.