Association of High-sensitivity C-reactive Protein Level with Obese Normal individuals in North Indian Population.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

Annals of African Medicine Pub Date : 2024-10-23 DOI:10.4103/aam.aam_140_23

Neeraja Shukla, Soni Singh, Shraddha Singh, Abhishek Shukla

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Abstract

Background: One of the major inflammatory markers, C-reactive protein (CRP), is often elevated in people who have had a heart attack, vascular problems, stroke, or sudden cardiac death. Obesity is associated with higher CRP levels because adipose tissue activates cytokines. Obesity and overweight increase the risk of heart disease, as does an elevated CRP level.

Purpose: The purpose of this study was to evaluate the association of high-sensitivity CRP (hs-CRP) level with obese normal individuals in North Indian population.

Materials and methods: This cross-sectional study included 50 individuals between the ages of 18 and 50 years who were overweight or obese. The degree of obesity was determined by anthropometric measurements. The patients' height, weight, waist circumference (WC), hip circumference, and blood pressure were measured. Enzyme-linked immunosorbent assay-based CRP level was determined from the blood.

Results: The mean WC (cm) was significantly higher in the obese (103.42 ± 9.79) than in the overweight (89.00 ± 8.72). The mean hip circumference (cm) was also significantly smaller in the obese group (99.95 ± 8.07) than in the overweight group (131.29 ± 15.82). The waist-to-hip ratio (WHR) was significantly more in the obese group (88.37%) than in the overweight group (0.00%). WC (cm), hip circumference (cm), WHR, systolic blood pressure (mmHg), and diastolic blood pressure (mmHg) were not significantly correlated with hs-CRP in overweight and obese participants.

Conclusion: Compared with obesity, hs-CRP was not related to obesity. A relationship between hs-CRP and WC, hip circumference, and WHR was not found.

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北印度人群高敏 C 反应蛋白水平与肥胖正常人的关系

背景：主要炎症指标之一的 C 反应蛋白 (CRP) 常常在心脏病发作、血管问题、中风或心脏性猝死患者中升高。肥胖与 CRP 水平升高有关，因为脂肪组织会激活细胞因子。肥胖和超重会增加患心脏病的风险，CRP 水平升高也会增加患心脏病的风险。目的：本研究旨在评估北印度人群中高敏 CRP（hs-CRP）水平与肥胖正常人的关系：这项横断面研究包括 50 名年龄在 18 岁至 50 岁之间的超重或肥胖者。肥胖程度通过人体测量来确定。对患者的身高、体重、腰围、臀围和血压进行了测量。通过酶联免疫吸附法测定血液中的 CRP 水平：结果：肥胖者的平均腰围（厘米）（103.42 ± 9.79）明显高于超重者（89.00 ± 8.72）。肥胖组的平均臀围（厘米）（99.95 ± 8.07）也明显小于超重组（131.29 ± 15.82）。肥胖组的腰臀比（WHR）（88.37%）明显高于超重组（0.00%）。超重和肥胖参与者的腰围（厘米）、臀围（厘米）、WHR、收缩压（毫米汞柱）和舒张压（毫米汞柱）与 hs-CRP 无明显相关性：结论：与肥胖相比，hs-CRP与肥胖无关。结论：与肥胖相比，hs-CRP 与肥胖无关，也未发现 hs-CRP 与腹围、臀围和 WHR 之间的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of African Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.