Insights into the effects of lanthanides on mammalian systems and potential applications

IF 7.7 2区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES
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引用次数: 0

Abstract

Lanthanides, a group of elements with unique chemical properties, have garnered significant attention for their varied biological effects, ranging from cytotoxic to protective, depending on concentration, cell type, and exposure conditions. This review provides a detailed examination of the biological interactions of lanthanides with mammalian systems, including humans, by exploring their impact on different cell lines and organisms. Through a systematic assessment of current research, this work highlights the dual nature of lanthanides, identifying them as both potential therapeutic agents and environmental toxins. Furthermore, it underscores the importance of understanding their mechanisms to mitigate health risks, particularly for those exposed occupationally or via environmental sources. The review concludes with an overview of knowledge gaps and future research directions necessary for unlocking the therapeutic potential of lanthanides while ensuring safety and sustainability in their applications.
深入了解镧系元素对哺乳动物系统的影响和潜在应用。
镧系元素是一组具有独特化学性质的元素,因其不同的生物效应而备受关注,根据浓度、细胞类型和接触条件的不同,其生物效应从细胞毒性到保护性不等。本综述通过探讨镧系元素对不同细胞系和生物体的影响,详细研究了镧系元素与包括人类在内的哺乳动物系统的生物相互作用。通过对当前研究的系统评估,本研究强调了镧系元素的双重性质,将其确定为潜在的治疗药物和环境毒素。此外,它还强调了了解镧系元素机理以降低健康风险的重要性,尤其是对于那些因职业原因或通过环境来源而接触镧系元素的人来说。综述最后概述了知识差距和未来研究方向,这对于释放镧系元素的治疗潜力,同时确保其应用的安全性和可持续性十分必要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Environmental Research
Environmental Research 环境科学-公共卫生、环境卫生与职业卫生
CiteScore
12.60
自引率
8.40%
发文量
2480
审稿时长
4.7 months
期刊介绍: The Environmental Research journal presents a broad range of interdisciplinary research, focused on addressing worldwide environmental concerns and featuring innovative findings. Our publication strives to explore relevant anthropogenic issues across various environmental sectors, showcasing practical applications in real-life settings.
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