Saline based microfluidic soft pressure sensor utilizing a three-dimensional focused electric field for motion and healthcare monitoring.

IF 10.7 1区 生物学 Q1 BIOPHYSICS
Biosensors and Bioelectronics Pub Date : 2025-01-01 Epub Date: 2024-10-21 DOI:10.1016/j.bios.2024.116868
Suhyeon Kim, Hyeonsu Woo, Seungbin Yoon, HyungGon Shin, Keehoon Kim, Geonhwee Kim, Geunbae Lim
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Abstract

This paper introduces the 'Spatially Focused Saline-based Pressure Sensor (SF-SaPS)', a novel soft microfluidic pressure sensor featuring a distinctive three-dimensional focusing structure. By critically reducing the cross-sectional area of the microchannel at the focused structure, the SF-SaPS achieves excellent sensitivity to pressure within the sensing region. With the spatially focused region, the SF-SaPS could detect a wide range of pressure from gentle touches to human weight, which is typically unachievable with low-conductivity sensing media such as saline, a medium inherently safe for human use. Beyond its sensitivity, the SF-SaPS exhibits sensing performance and stability comparable with conventional liquid metal-based pressure sensors. Our sensor demonstrated minimal signal drift, a rapid response time of 70 ms under cyclic loading, and 20-day long-term stability tests immersed in water. Additionally, the sensor possesses a transparency advantage unattainable by liquid metal sensors as we utilized transparent polymers and saline. A unique advantage of the SF-SaPS lies in its selective spatial and mechanical sensitivity; as the electrical resistance is highly dependent on changes in the cross-sectional area of the microchannels, the sensor has superior pressure sensitivity compared to bending and strain. Finally, various application examples highlight the SF-SaPS's advantages. By configuring the sensor in a two-axis array, the SF-SaPS facilitates pressure mapping across a plane. Additionally, it proves effective in healthcare monitoring, from radial pulse to finger movements. In conclusion, the SF-SaPS's combination of performance, stability, biocompatibility, and transparency positions this sensor as a versatile tool for applications extending beyond healthcare, as demonstrated in this study.

基于生理盐水的微流体软压力传感器,利用三维聚焦电场进行运动和医疗监控。
本文介绍了 "空间聚焦盐基压力传感器(SF-SaPS)",这是一种新型软微流体压力传感器,具有独特的三维聚焦结构。通过大幅缩小聚焦结构处微通道的横截面积,SF-SaPS 实现了对传感区域内压力的出色灵敏度。通过空间聚焦区域,SF-SaPS 可以检测到从轻触到人体重量的各种压力,而这是生理盐水等低传导性传感介质通常无法实现的,因为生理盐水本质上是一种对人体安全的介质。除了灵敏度之外,SF-SaPS 还具有与传统液态金属压力传感器相当的传感性能和稳定性。我们的传感器信号漂移极小,在循环加载下的快速响应时间为 70 毫秒,并在水中进行了 20 天的长期稳定性测试。此外,由于我们使用了透明聚合物和生理盐水,该传感器还具有液态金属传感器无法达到的透明度优势。SF-SaPS 的独特优势在于其选择性的空间和机械灵敏度;由于电阻高度依赖于微通道横截面积的变化,传感器的压力灵敏度优于弯曲和应变。最后,各种应用实例凸显了 SF-SaPS 的优势。通过将传感器配置为双轴阵列,SF-SaPS 可以方便地绘制平面压力图。此外,从径向脉搏到手指运动,SF-SaPS 还能有效监测医疗保健。总之,SF-SaPS 集性能、稳定性、生物兼容性和透明性于一身,使其成为医疗保健以外应用的多功能工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biosensors and Bioelectronics
Biosensors and Bioelectronics 工程技术-电化学
CiteScore
20.80
自引率
7.10%
发文量
1006
审稿时长
29 days
期刊介绍: Biosensors & Bioelectronics, along with its open access companion journal Biosensors & Bioelectronics: X, is the leading international publication in the field of biosensors and bioelectronics. It covers research, design, development, and application of biosensors, which are analytical devices incorporating biological materials with physicochemical transducers. These devices, including sensors, DNA chips, electronic noses, and lab-on-a-chip, produce digital signals proportional to specific analytes. Examples include immunosensors and enzyme-based biosensors, applied in various fields such as medicine, environmental monitoring, and food industry. The journal also focuses on molecular and supramolecular structures for enhancing device performance.
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