Fabrication of Zinc(II) Mediated Poly(Acrylamide Co Acrylic Acid) Hydrogel with Thixotropic and Tribological Properties.

IF 4.2 3区 化学 Q2 POLYMER SCIENCE
Paresh Nageshwar, Suraj W Wajge, Gopal Lal Dhakar, Avinash A Thakre, Swapnil Tripathi, Shiva Singh, Pradip K Maji, Chayan Das
{"title":"Fabrication of Zinc(II) Mediated Poly(Acrylamide Co Acrylic Acid) Hydrogel with Thixotropic and Tribological Properties.","authors":"Paresh Nageshwar, Suraj W Wajge, Gopal Lal Dhakar, Avinash A Thakre, Swapnil Tripathi, Shiva Singh, Pradip K Maji, Chayan Das","doi":"10.1002/marc.202400670","DOIUrl":null,"url":null,"abstract":"<p><p>Hydrogels have emerged as promising candidates for biomedical applications, such as replacing natural articular cartilage, owing to their unique viscoelastic properties. However, sufficient mechanical properties, self-healing ability, and adhesive nature are some issues limiting its application window. Here, a facile one-pot synthesis of dual cross-linked zinc-coordinated copolymer hydrogels is presented. The network structure of the copolymer hydrogels is strategically developed via dynamic and reversible physical cross-linking by Zn<sup>2+</sup> ions and simultaneous covalent cross-linking through a covalent cross-linker viz methylene bisacrylamide. Fourier-transform infrared (FTIR), X-ray diffraction (XRD) scanning electron microscopy (SEM), and Brunauer-Emmett-Teller (BET) analysis have thoroughly characterized the structure of the synthesized hydrogels. The introduction of Zn<sup>2+</sup> offers dynamic and reversible complexation, leading to excellent mechanical properties and self-healing features. Moreover, the percentage of the equilibrium water content of zinc-coordinated copolymer hydrogel samples is comparable with that of natural articular cartilage. The Shear sliding study shows the dominant adhesive behavior of HGel-Zn(NO<sub>3</sub>)<sub>2</sub> sample compared to the parent HGel sample. This facile dual cross-linked hydrogel, HGel-Zn(NO<sub>3</sub>)<sub>2,</sub> with a combination of good mechanical properties, efficient self-recovery, adequate water content, and favorable adhesive nature, seems very promising to mimic the articular cartilage.</p>","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e2400670"},"PeriodicalIF":4.2000,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Macromolecular Rapid Communications","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/marc.202400670","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 0

Abstract

Hydrogels have emerged as promising candidates for biomedical applications, such as replacing natural articular cartilage, owing to their unique viscoelastic properties. However, sufficient mechanical properties, self-healing ability, and adhesive nature are some issues limiting its application window. Here, a facile one-pot synthesis of dual cross-linked zinc-coordinated copolymer hydrogels is presented. The network structure of the copolymer hydrogels is strategically developed via dynamic and reversible physical cross-linking by Zn2+ ions and simultaneous covalent cross-linking through a covalent cross-linker viz methylene bisacrylamide. Fourier-transform infrared (FTIR), X-ray diffraction (XRD) scanning electron microscopy (SEM), and Brunauer-Emmett-Teller (BET) analysis have thoroughly characterized the structure of the synthesized hydrogels. The introduction of Zn2+ offers dynamic and reversible complexation, leading to excellent mechanical properties and self-healing features. Moreover, the percentage of the equilibrium water content of zinc-coordinated copolymer hydrogel samples is comparable with that of natural articular cartilage. The Shear sliding study shows the dominant adhesive behavior of HGel-Zn(NO3)2 sample compared to the parent HGel sample. This facile dual cross-linked hydrogel, HGel-Zn(NO3)2, with a combination of good mechanical properties, efficient self-recovery, adequate water content, and favorable adhesive nature, seems very promising to mimic the articular cartilage.

制备具有触变性和摩擦学特性的锌(II)介导聚丙烯酰胺-丙烯酸水凝胶。
水凝胶因其独特的粘弹性能,已成为生物医学应用(如替代天然关节软骨)的理想候选材料。然而,足够的机械性能、自愈合能力和粘合性等问题限制了水凝胶的应用。本文介绍了双交联锌配位共聚物水凝胶的简单单锅合成方法。共聚物水凝胶的网络结构是通过 Zn2+ 离子的动态可逆物理交联和共价交联剂(即亚甲基双丙烯酰胺)的同步共价交联而形成的。傅立叶变换红外光谱(FTIR)、X 射线衍射(XRD)、扫描电子显微镜(SEM)和布鲁纳尔-艾美特-泰勒(BET)分析彻底确定了合成水凝胶的结构特征。Zn2+ 的引入提供了动态和可逆的络合,带来了优异的机械性能和自愈合特性。此外,锌配位共聚物水凝胶样品的平衡含水量百分比与天然关节软骨相当。剪切滑动研究表明,与母体 HGel 样品相比,HGel-Zn(NO3)2 样品的粘附行为占主导地位。HGel-Zn(NO3)2 这种简便的双交联水凝胶具有良好的机械性能、高效的自我恢复能力、充足的含水量和有利的粘附性,似乎很有希望模拟关节软骨。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Macromolecular Rapid Communications
Macromolecular Rapid Communications 工程技术-高分子科学
CiteScore
7.70
自引率
6.50%
发文量
477
审稿时长
1.4 months
期刊介绍: Macromolecular Rapid Communications publishes original research in polymer science, ranging from chemistry and physics of polymers to polymers in materials science and life sciences.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信