Associations of ambient particulate matter and household fuel use with chronic liver disease in China: A nationwide analysis

IF 10.3 1区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environment International Pub Date : 2024-10-23 DOI:10.1016/j.envint.2024.109083

Yongyue Chen, Chenyu Zhao, Yi Zhang, Yan Lin, Guibin Shen, Nana Wang, Xiaocan Jia, Yongli Yang

{"title":"Associations of ambient particulate matter and household fuel use with chronic liver disease in China: A nationwide analysis","authors":"Yongyue Chen, Chenyu Zhao, Yi Zhang, Yan Lin, Guibin Shen, Nana Wang, Xiaocan Jia, Yongli Yang","doi":"10.1016/j.envint.2024.109083","DOIUrl":null,"url":null,"abstract":"<h3>Background</h3>Long-term effects of outdoor and indoor air pollution on chronic liver disease (CLD) remain unclear. Thus, the study was conducted to investigate the relationship between prolonged exposure to ambient particulate matter (PM<sub>1</sub>, PM<sub>2.5</sub> and PM<sub>10</sub>) and household fuel usage with CLD.<h3>Methods</h3>Data from the China Health and Retirement Longitudinal Study (CHARLS) covering the years 2011 to 2020 were employed. In the cross-sectional analysis, 16,680 participants were included, while 12,969 participants were enrolled in the longitudinal study. The associations between various sizes of particulate matter and CLD were elucidated using logistic regression model and generalized linear-mixed models. Additionally, the additive effects of ambient particulate matter (PM) levels and the utilization of solid fuels for cooking were investigated, with a comparison of effect sizes between converted and non-converted fuel types.<h3>Results</h3>Over a 10-year follow-up period, 746 (5.75 %) individuals developed CLD. For a 1-year average concentrations, PM<sub>1</sub>, PM<sub>2.5</sub> and PM<sub>10</sub> were each linked to a 1.549 (95 %CI:1.522–1.576), 1.296 (95 %CI:1.276–1.317) and 1.134 (95 %CI:1.118–1.150) fold risk of incident CLD per 10 μg/m<sup>3</sup> increase, respectively. A similar effect of PM concentrations over a 2-year period on CLD was observed. Moreover, simultaneous exposure to ambient PM and solid fuels is associated with an increased risk of CLD. Those who continue using solid fuels may face a higher risk of CLD compared to individuals who switch to cleaner cooking fuels. Female participants, smokers, and individuals with shorter sleep duration and multiple chronic diseases exhibited slightly stronger effects.<h3>Conclusion</h3>Long-term exposure to varying sizes of PM (PM<sub>1,</sub> PM<sub>2.5</sub>, PM<sub>10</sub>) has been linked to an elevated risk of CLD incidence. Co-exposure to ambient PM and solid fuels is associated with higher health risks.","PeriodicalId":308,"journal":{"name":"Environment International","volume":null,"pages":null},"PeriodicalIF":10.3000,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environment International","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1016/j.envint.2024.109083","RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Long-term effects of outdoor and indoor air pollution on chronic liver disease (CLD) remain unclear. Thus, the study was conducted to investigate the relationship between prolonged exposure to ambient particulate matter (PM₁, PM_2.5 and PM₁₀) and household fuel usage with CLD.

Methods

Data from the China Health and Retirement Longitudinal Study (CHARLS) covering the years 2011 to 2020 were employed. In the cross-sectional analysis, 16,680 participants were included, while 12,969 participants were enrolled in the longitudinal study. The associations between various sizes of particulate matter and CLD were elucidated using logistic regression model and generalized linear-mixed models. Additionally, the additive effects of ambient particulate matter (PM) levels and the utilization of solid fuels for cooking were investigated, with a comparison of effect sizes between converted and non-converted fuel types.

Results

Over a 10-year follow-up period, 746 (5.75 %) individuals developed CLD. For a 1-year average concentrations, PM₁, PM_2.5 and PM₁₀ were each linked to a 1.549 (95 %CI:1.522–1.576), 1.296 (95 %CI:1.276–1.317) and 1.134 (95 %CI:1.118–1.150) fold risk of incident CLD per 10 μg/m³ increase, respectively. A similar effect of PM concentrations over a 2-year period on CLD was observed. Moreover, simultaneous exposure to ambient PM and solid fuels is associated with an increased risk of CLD. Those who continue using solid fuels may face a higher risk of CLD compared to individuals who switch to cleaner cooking fuels. Female participants, smokers, and individuals with shorter sleep duration and multiple chronic diseases exhibited slightly stronger effects.

Conclusion

Long-term exposure to varying sizes of PM (PM_1, PM_2.5, PM₁₀) has been linked to an elevated risk of CLD incidence. Co-exposure to ambient PM and solid fuels is associated with higher health risks.

查看原文本刊更多论文

中国环境颗粒物和家庭燃料使用与慢性肝病的关系：全国性分析

背景室外和室内空气污染对慢性肝病（CLD）的长期影响尚不清楚。因此，本研究对长期暴露于环境颗粒物（PM1、PM2.5 和 PM10）和家庭燃料使用与慢性肝病之间的关系进行了调查。方法采用中国健康与退休纵向研究（CHARLS）2011 年至 2020 年的数据。在横断面分析中，纳入了 16,680 名参与者，而在纵向研究中纳入了 12,969 名参与者。研究采用逻辑回归模型和广义线性混合模型阐明了各种粒径的颗粒物与慢性阻塞性肺病之间的关系。此外，研究还调查了环境颗粒物（PM）水平和使用固体燃料做饭的叠加效应，并比较了转换燃料和未转换燃料类型之间的效应大小。就 1 年的平均浓度而言，PM1、PM2.5 和 PM10 每增加 10 μg/m3 分别与 1.549（95 %CI：1.522-1.576）、1.296（95 %CI：1.276-1.317）和 1.134（95 %CI：1.118-1.150）倍的 CLD 发病风险有关。在为期两年的时间里，可吸入颗粒物浓度对慢性肺部疾病也有类似的影响。此外，同时接触环境中的可吸入颗粒物和固体燃料会增加慢性肺部疾病的风险。与改用清洁烹饪燃料的人相比，继续使用固体燃料的人可能面临更高的慢性慢性阻塞性肺病风险。女性参与者、吸烟者以及睡眠时间较短和患有多种慢性疾病的人受到的影响略大。同时暴露于环境可吸入颗粒物和固体燃料与更高的健康风险有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Environment International 环境科学-环境科学

CiteScore

21.90

自引率

3.40%

发文量

734

审稿时长

2.8 months

期刊介绍： Environmental Health publishes manuscripts focusing on critical aspects of environmental and occupational medicine, including studies in toxicology and epidemiology, to illuminate the human health implications of exposure to environmental hazards. The journal adopts an open-access model and practices open peer review. It caters to scientists and practitioners across all environmental science domains, directly or indirectly impacting human health and well-being. With a commitment to enhancing the prevention of environmentally-related health risks, Environmental Health serves as a public health journal for the community and scientists engaged in matters of public health significance concerning the environment.