Characterization of lingual microbiota in pediatric geographic tongue.

The Turkish journal of pediatrics Pub Date : 2024-10-07 DOI:10.24953/turkjpediatr.2024.4638

Yi You, Yuan He, Peicheng Huang

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引用次数: 0

Abstract

Background: Geographic tongue is an oral mucosal lesion affecting the tongue. The association between geographic tongue and the mucosal microbiota in children remains unclear.

Method: To characterize the feature of lingual microbiota in pediatric geographic tongue, lingual swabs were collected from lesion sites and healthy sites of 25 patients with geographic tongue (14 males and 11 females; age 5.21 ±2.94 years) and 19 controls (10 males and 9 females; age 5.31±2.82 years). DNA was extracted and the 16S rRNA was amplificated, sequenced and analyzed.

Results: The lingual microbiota composition was significantly different between children with geographic tongue and the healthy cohort; Streptobacillus was reduced in geographic tongue, while Catonella, Bacillus and Oribacterium were overrepresented. When the lesions and the normal mucosa were compared, an increased abundance of Prevotella oris was observed.

Conclusion: Our results provided new insight into the association between oral microbiota and pediatric geographic tongue.

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小儿地理舌的舌微生物群特征。

背景介绍地包天是一种影响舌头的口腔黏膜病变。儿童地包天舌与粘膜微生物群之间的关系仍不清楚：为了描述小儿地包天舌舌黏膜微生物区系的特征，研究人员从25名地包天舌患者（男14名，女11名；年龄5.21±2.94岁）和19名对照组（男10名，女9名；年龄5.31±2.82岁）的病变部位和健康部位采集了舌拭子。研究人员提取了 DNA，并对 16S rRNA 进行了扩增、测序和分析：结果：舌炎患儿的舌微生物群组成与健康人群有显著差异；舌炎患儿的链球菌减少，而卡托奈氏菌、芽孢杆菌和奥里布氏菌的比例较高。将病变粘膜与正常粘膜进行比较，发现口腔普雷沃特氏菌的数量有所增加：我们的研究结果为了解口腔微生物群与小儿地包天之间的关系提供了新的视角。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Turkish journal of pediatrics

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