Pulmonary Lymphatics History, Anatomy, and Pathophysiology: Emerging Knowledge and a Look to the Future.

Lymphology Pub Date : 2024-01-01
B Kelly, S Daley
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Abstract

Central lymphatic disorders of the lung have not received intense investigation. Lymphatic system physiology is presented in the context of historical developments and basic lung lymphatic anatomy is reviewed followed by emerging characteristics of primary and secondary pathophysiological disturbances of lymphatic involvement in a number of pulmonary diseases including Gorham-Stout disease, pulmonary edema and infections and inflammatory conditions including lymphangioleiomyomatosis (LAM). The future includes potential molecular targeting of lymphangiogenesis or lymphatic vessels for interventional occlusion. This article is an amalgamation of presentations at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease and as part of a Special Symposium on the Lymphatic system of the Heart and Lung in Health and Disease at the 26th International Congress of Lymphology meeting held in Barcelona, Spain, September 2017, which has been updated to 2024.

肺淋巴管的历史、解剖和病理生理学:新兴知识与未来展望。
肺中枢淋巴系统疾病尚未得到深入研究。淋巴系统生理学在历史发展的背景下进行介绍,并回顾了基本的肺部淋巴解剖,随后介绍了淋巴参与多种肺部疾病(包括戈勒姆-斯托特病、肺水肿、感染和炎症,包括淋巴管瘤病(LAM))的原发性和继发性病理生理紊乱的新特点。未来的研究还包括潜在的分子靶向淋巴管生成或淋巴管介入性闭塞。本文综合了2023年意大利热那亚ISL国际淋巴大会上关于健康和疾病中的中央和区域淋巴系统的特别研讨会上的发言,以及2017年9月在西班牙巴塞罗那举行的第26届国际淋巴大会上关于健康和疾病中的心肺淋巴系统的特别研讨会上的发言,现已更新至2024年。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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