Glucose inhibitor tubes in Croatian laboratories: are we doing well?

Biochemia medica Pub Date : 2024-10-15 DOI:10.11613/BM.2024.030901

Alen Vrtarić, Nora Nikolac Gabaj, Ivana Ćelap

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Abstract

Introduction: Reliable and accurate measurement of blood glucose concentration is of crucial importance for making clinical decisions in diagnosis diabetes, gestational diabetes and impaired fasting glucose tolerance.

Materials and methods: Survey was performed in form of questionnaire. Questionnaire was sent to all Croatian laboratories (N = 204) in electronic form using SurveyMonkey cloud-based software (SurveyMonkey, Inc., San Mateo, USA) as an extra-analytical module of the Croatian EQA (External Quality Assessment) provider Croatian center for external quality assessment (CROQALM) in June 2023.

Results: In total 148 (73%) of laboratories responded to the survey. Large proportion of laboratories never use glucose inhibitor tubes for random glucose measurement (more than half) or for glucose function tests (one quarter). Only three laboratories use recommended glycolysis inhibitor citrate. Many other inhibitors are also used, even if some of them are not recommended for plasma glucose measurement. Glucose is almost never (93%) sampled on ice when glucose inhibitor tube is not available.

Conclusions: Laboratories in Croatia do not follow the recommended procedures regarding glycolysis inhibitors for glucose determination.

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克罗地亚实验室的葡萄糖抑制剂试管：我们做得好吗？

导言：可靠而准确的血糖浓度测量对于诊断糖尿病、妊娠糖尿病和空腹糖耐量受损的临床决策至关重要：调查以问卷形式进行。作为克罗地亚外部质量评估（EQA）提供商克罗地亚外部质量评估中心（CROQALM）于2023年6月推出的一个分析外模块，调查问卷以电子形式通过SurveyMonkey云端软件（SurveyMonkey, Inc：共有 148 家（73%）实验室对调查做出了回应。大部分实验室从未使用葡萄糖抑制管进行随机葡萄糖测量（超过一半）或葡萄糖功能测试（四分之一）。只有三家实验室使用推荐的糖酵解抑制剂柠檬酸盐。其他许多抑制剂也被使用，即使其中有些抑制剂不推荐用于血浆葡萄糖测量。在没有葡萄糖抑制剂试管的情况下，几乎从未（93%）在冰上进行葡萄糖采样：结论：克罗地亚的实验室没有按照建议的程序使用糖酵解抑制剂进行葡萄糖测定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biochemia medica

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