Tatsuya Tada, Satoshi Oshiro, Naeko Mizutani, Koji Sato, Nang Sarm Hom, Pan Ei Soe, Thi Thi Htoon, Htay Htay Tin, Teruo Kirikae
{"title":"Emergence of drug-resistant <i>Elizabethkingia anophelis</i> clinical isolates in Myanmar.","authors":"Tatsuya Tada, Satoshi Oshiro, Naeko Mizutani, Koji Sato, Nang Sarm Hom, Pan Ei Soe, Thi Thi Htoon, Htay Htay Tin, Teruo Kirikae","doi":"10.1099/jmm.0.001917","DOIUrl":null,"url":null,"abstract":"<p><p>Seven drug-resistant <i>Elizabethkingia anophelis</i> isolates were obtained from inpatients in three medical settings in Myanmar between February 2017 and January 2021. All isolates were resistant to β-lactams and colistin. Among these, four isolates were resistant to amikacin with minimum inhibitory concentration (MIC) of ≥64 µg ml<sup>-1</sup>. Six of the seven isolates harboured genes encoding intrinsic β-lactamases, including <i>bla</i> <sub>B</sub>, <i>bla</i> <sub>CME</sub> and <i>bla</i> <sub>GOB</sub>, whereas one isolate harboured <i>bla</i> <sub>B</sub>, <i>bla</i> <sub>CME</sub> and an incomplete <i>bla</i> <sub>GOB</sub> gene. Phylogenetic analysis based on whole-genome sequences revealed that several <i>E. anophelis</i> isolates in Myanmar formed their own clusters, whereas others were similar to isolates found in the USA. This is the first report of the emergence of <i>Elizabethkingia</i> species in Myanmar.</p>","PeriodicalId":94093,"journal":{"name":"Journal of medical microbiology","volume":"73 10","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of medical microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1099/jmm.0.001917","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Seven drug-resistant Elizabethkingia anophelis isolates were obtained from inpatients in three medical settings in Myanmar between February 2017 and January 2021. All isolates were resistant to β-lactams and colistin. Among these, four isolates were resistant to amikacin with minimum inhibitory concentration (MIC) of ≥64 µg ml-1. Six of the seven isolates harboured genes encoding intrinsic β-lactamases, including blaB, blaCME and blaGOB, whereas one isolate harboured blaB, blaCME and an incomplete blaGOB gene. Phylogenetic analysis based on whole-genome sequences revealed that several E. anophelis isolates in Myanmar formed their own clusters, whereas others were similar to isolates found in the USA. This is the first report of the emergence of Elizabethkingia species in Myanmar.