Projecting the Dynamic Trends of Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome: Modeling the Epidemic in Sichuan Province, China.

Yuan Li, Qin Xi Liu, Rong Sheng Luan, Yi Yang, Tao Wu, Bi Hui Yang
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Abstract

Objective: Our study aimed to provide a comprehensive overview of the current status and dynamic trends of the human immunodeficiency virus (HIV) prevalence in Sichuan, the second most heavily affected province in China, and to explore future interventions.

Methods: The epidemiological, behavioral, and population census data from multiple sources were analyzed to extract inputs for an acquired immunodeficiency syndrome (AIDS) epidemic model (AEM). Baseline curves, derived from historical trends in HIV prevalence, were used, and the AEM was employed to examine future intervention scenarios.

Results: In 2015, the modeled data suggested an adult HIV prevalence of 0.191% in Sichuan, with an estimated 128,766 people living with HIV/AIDS and 16,983 individuals with newly diagnosed infections. Considering current high-risk behaviors, the model predicts an increase in the adult prevalence to 0.306% by 2025, projecting an estimated 212,168 people living with HIV/AIDS and 16,555 individuals with newly diagnosed infections.

Conclusion: Heterosexual transmission will likely emerge as the primary mode of AIDS transmission in Sichuan. Furthermore, we anticipate a stabilization in the incidence of AIDS with a concurrent increase in prevalence. Implementing comprehensive intervention measures aimed at high-risk groups could effectively alleviate the spread of AIDS in Sichuan.

预测人类免疫缺陷病毒/获得性免疫缺陷综合征的动态趋势:中国四川省疫情模型。
研究目的我们的研究旨在全面概述中国艾滋病疫情第二大省四川的人类免疫缺陷病毒(HIV)流行现状和动态趋势,并探讨未来的干预措施:方法:通过分析多种来源的流行病学、行为学和人口普查数据,提取获得性免疫缺陷综合征(艾滋病)流行模型(AEM)的输入数据。根据艾滋病病毒感染率的历史趋势得出基线曲线,并利用该模型对未来的干预方案进行研究:结果:模型数据显示,2015 年四川成人艾滋病感染率为 0.191%,估计有 128,766 名艾滋病感染者和 16,983 名新确诊感染者。考虑到目前的高危行为,模型预测到 2025 年,成人感染率将上升到 0.306%,预计感染者将达到 212,168 人,新确诊感染者将达到 16,555 人:结论:异性传播将成为四川艾滋病的主要传播方式。此外,我们预计艾滋病发病率将趋于稳定,流行率将同时上升。针对高危人群采取综合干预措施,可有效缓解艾滋病在四川的传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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