Relationships Among Stress, Diabetes Distress, and Biomarkers in Children with Type 1 Diabetes Mellitus from Diverse Income and Racial Backgrounds.

IF 2.5 4区 医学 Q2 HEALTH POLICY & SERVICES
Journal of Pediatric Health Care Pub Date : 2025-01-01 Epub Date: 2024-10-10 DOI:10.1016/j.pedhc.2024.08.012
Sara L Davis, Sarah S Jaser, Nataliya Ivankova, Marti Rice
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引用次数: 0

Abstract

Introduction: The purpose of this quantitative study was to consider factors that may negatively impact glycemic levels in Black and White children 8-12 years old with a diagnosis of type 1 diabetes mellitus.

Method: Perceived stress, diabetes distress, morning and afternoon salivary cortisol, inflammatory biomarkers, and hemoglobin A1c (HbA1c) were measured in this quantitative, cross-sectional phase of a larger, mixed methods study. Thirty-four children and their parents completed self-report surveys, and children provided blood and salivary samples, to examine effect sizes of relationships among variables of interest.

Results: Most children did not meet ADA recommendations for HbA1c. HbA1c was higher in Black children. Medium-to-large effects were noted between perceived stress and HbA1c. Cortisol and IL-8 may mediate the relationship between perceived stress and HbA1c in children.

Discussion: Understanding causes of elevated glycemic levels in children, especially from low-income and underrepresented populations, may help tailor diabetes management interventions to improve health outcomes.

来自不同收入和种族背景的 1 型糖尿病患儿的压力、糖尿病困扰和生物标志物之间的关系。
简介:本定量研究的目的是考虑可能对确诊为 1 型糖尿病的 8-12 岁黑人和白人儿童血糖水平产生负面影响的因素:这项定量研究的目的是考虑可能对确诊为 1 型糖尿病的 8-12 岁黑人和白人儿童的血糖水平产生负面影响的因素:本研究是一项大型混合方法研究的横断面定量阶段,测量了感知压力、糖尿病困扰、上午和下午唾液皮质醇、炎症生物标志物和血红蛋白 A1c (HbA1c)。34 名儿童及其家长完成了自我报告调查,儿童提供了血液和唾液样本,以研究相关变量之间关系的效应大小:结果:大多数儿童的 HbA1c 值不符合美国糖尿病协会的建议。黑人儿童的 HbA1c 更高。在感知压力和 HbA1c 之间存在中度到大型效应。皮质醇和IL-8可能是儿童感知到的压力与HbA1c之间关系的中介:讨论:了解儿童血糖水平升高的原因,尤其是来自低收入和代表性不足人群的原因,有助于调整糖尿病管理干预措施,改善健康状况。
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来源期刊
CiteScore
3.40
自引率
10.70%
发文量
140
审稿时长
24 days
期刊介绍: The Journal of Pediatric Health Care, the official journal of the National Association of Pediatric Nurse Practitioners, provides scholarly clinical information and research regarding primary, acute and specialty health care for children of newborn age through young adulthood within a family-centered context. The Journal disseminates multidisciplinary perspectives on evidence-based practice and emerging policy, advocacy and educational issues that are of importance to all healthcare professionals caring for children and their families.
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