Weekly transcranial magnetic stimulation (TMS) maintenance: a case series.

IF 3 4区医学 Q2 PSYCHIATRY

World Journal of Biological Psychiatry Pub Date : 2024-11-01 Epub Date: 2024-10-16 DOI:10.1080/15622975.2024.2416385

Marzena Rybak, Gregory M Peterson, Saxby Pridmore, Yvonne Turnier-Shea, Karen Byrne, Tae Dillon

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引用次数: 0

Abstract

Objectives: To report an observational case series study of sustained, once-weekly continuation transcranial magnetic stimulation (TMS) provided with the aim of maintaining remission in patients with major depressive disorder (MDD).

Methods: Once-weekly TMS treatments were provided to 7 patients (median age of 54 years) with chronic relapsing MDD: 4 of these patients entered the study in remission according to the six-item Hamilton depression rating scale (HAM-D6) and were followed for more than 12 months, and 3 patients entered the study in HAM-D6 partial remission/relapse and were followed for more than 6 months.

Results: All patients remained clinically well throughout the study. The 4 patients who entered in remission were maintained in HAM-D6 remission or partial remission. The 3 patients who entered the study in HAM-D6 partial remission/relapse were maintained free of clinical depression.

Conclusions: Seven patients with a history of relapsing MDD were provided with once-weekly continuation TMS and remained free of clinical relapse for more than 6 or 12 months. While the study had a small sample size, the clear, real-world outcomes warrant further investigation.

查看原文本刊更多论文

每周经颅磁刺激（TMS）维持治疗：病例系列。

目的：报告一项观察性病例系列研究：报告一项观察性病例系列研究，研究对象是以维持重度抑郁障碍（MDD）患者病情缓解为目的的持续性、每周一次的经颅磁刺激（TMS）：7名慢性复发性重度抑郁症患者（中位年龄54岁）接受了每周一次的经颅磁刺激治疗：其中4名患者根据汉密尔顿抑郁评分量表（HAM-D6）的6个项目进入研究，并接受了12个月以上的随访；3名患者在HAM-D6部分缓解/复发时进入研究，并接受了6个月以上的随访：在整个研究过程中，所有患者的临床症状均保持良好。结果：在整个研究过程中，所有患者的临床状况都保持良好。4 名患者在病情缓解时加入研究，并一直保持 HAM-D6 缓解或部分缓解。3名进入研究时处于HAM-D6部分缓解/复发状态的患者一直没有临床抑郁症：结论：7 名有复发性 MDD 病史的患者接受了每周一次的持续 TMS 治疗，并在 6 个月或 12 个月内未出现临床复发。虽然这项研究的样本量较小，但其明确的实际结果值得进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Biological Psychiatry 医学-精神病学

CiteScore

7.00

自引率

3.20%

发文量

审稿时长

6-12 weeks

期刊介绍： The aim of The World Journal of Biological Psychiatry is to increase the worldwide communication of knowledge in clinical and basic research on biological psychiatry. Its target audience is thus clinical psychiatrists, educators, scientists and students interested in biological psychiatry. The composition of The World Journal of Biological Psychiatry , with its diverse categories that allow communication of a great variety of information, ensures that it is of interest to a wide range of readers. The World Journal of Biological Psychiatry is a major clinically oriented journal on biological psychiatry. The opportunity to educate (through critical review papers, treatment guidelines and consensus reports), publish original work and observations (original papers and brief reports) and to express personal opinions (Letters to the Editor) makes The World Journal of Biological Psychiatry an extremely important medium in the field of biological psychiatry all over the world.