Effect of Low Protein Diet on Patients with Cardiovascular Disease: A Systematic Review and Meta-Analysis.

IF 1.3 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Iranian Journal of Public Health Pub Date : 2024-08-01 DOI:10.18502/ijph.v53i8.16275

Mingtao Ding, Lei Liu

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引用次数: 0

Abstract

Background: Low protein diet plays an important role in cardiovascular diseases. However, exact role is unclear so far. We aimed to find out the effect of low protein diet on patients with cardiovascular disease.

Methods: The PRISMA guidelines were followed throughout the research project until 10th Apr 2023. MeSH phrases and Boolean operators were used to search PubMed for suitable studies. The entire estimate was expressed as a 95% confidence interval around the mean difference. The model was picked because of the discrepancies found in the research. Choi's Q test and I² statistics were used to determine the degree of variation between experiments. The funnel plot was used to qualitatively examine the publishing bias.

Results: Low-protein diets have a greater impact on waist circumference [-8.82 (-9.51, -8.13), P<0000.1] and high-density lipoprotein (HDL) [-0.05 (-0.07, -0.03), P<0000.1] alteration than non-LPD diets, as measured by the standard mean difference (SMD). Further, significant changes were observed in weight loss [1.51 (1.25, 1.77), P<0.00001], BMI, [0.46 (0.25, 0.67), P<0.0001], change systolic [2.48 (1.20, 3.77), P=0.0002] and diastolic blood pressure [1.49 (0.72, 2.26), P=0.0002], low density lipoprotein [0.09 (0.06, 0.12), P<0.00001], triglyceride [0.52 (0.49, 0.55), P<0.00001], in non-LPD group as compared to LPD group.

Conclusion: The results indicated the role of low protein diet on patients with cardiovascular disease.

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低蛋白饮食对心血管疾病患者的影响：系统回顾与元分析》。

背景：低蛋白饮食在心血管疾病中扮演着重要角色。然而，其确切作用至今尚不清楚。我们旨在了解低蛋白饮食对心血管疾病患者的影响：方法：在 2023 年 4 月 10 日之前，整个研究项目都遵循 PRISMA 指南。使用 MeSH 词组和布尔运算符在 PubMed 上搜索合适的研究。整个估计值以平均差异的 95% 置信区间表示。之所以选择该模型，是因为在研究中发现了差异。崔氏 Q 检验和 I2 统计用于确定实验之间的差异程度。漏斗图用于定性检查出版偏差：结果：低蛋白膳食对腰围[-8.82（-9.51，-8.13），PPPP=0.0002]和舒张压[1.49（0.72，2.26），P=0.0002]、低密度脂蛋白[0.09（0.06，0.12），PPConclusion]的影响更大：结果表明，低蛋白饮食对心血管疾病患者有一定作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Iranian Journal of Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

2.20

自引率

7.10%

发文量

300

审稿时长

3-8 weeks

期刊介绍： Iranian Journal of Public Health has been continuously published since 1971, as the only Journal in all health domains, with wide distribution (including WHO in Geneva and Cairo) in two languages (English and Persian). From 2001 issue, the Journal is published only in English language. During the last 41 years more than 2000 scientific research papers, results of health activities, surveys and services, have been published in this Journal. To meet the increasing demand of respected researchers, as of January 2012, the Journal is published monthly. I wish this will assist to promote the level of global knowledge. The main topics that the Journal would welcome are: Bioethics, Disaster and Health, Entomology, Epidemiology, Health and Environment, Health Economics, Health Services, Immunology, Medical Genetics, Mental Health, Microbiology, Nutrition and Food Safety, Occupational Health, Oral Health. We would be very delighted to receive your Original papers, Review Articles, Short communications, Case reports and Scientific Letters to the Editor on the above mentioned research areas.