A systematic review and meta-analysis of effect of leucocyte- and platelet-rich fibrin on dental extraction.

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Medicina Oral Patologia Oral Y Cirugia Bucal Pub Date : 2024-11-01 DOI:10.4317/medoral.26724

X Wang, F Xin, S Zhou

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Abstract

Background: Dental extraction is the most common oral surgery, but it leads to the remodelling of the socket, such that an implant is required for repair. We performed meta-analysis to determine whether leucocyte- and platelet-rich fibrin (L-PRF) improves dental extraction.

Material and methods: Following a search of Scopus, Web of science, ProQuest and PubMed, six relevant studies were included (239 patients treated with L-PRF after dental extraction).

Results: The results provide higher percentage of bone formation after dental extraction in L-PRF implant patients with a mean difference of -13.16 (-15.89, -10.43) than control. Socket filling and horizontal width were also higher in the L-PRF implant group. A sub-group meta-analysis showed a significantly higher healing index 7 and 14 days after dental extraction in the L-PRF-treated group. The VAS score for pain stimuli was lower in the L-PRF group with a mean difference of 1.26 (1.00, 1.51) than control group; the difference in the heterogeneity of the studies was significant.

Conclusions: These results show that L-PRF prevents ridge formation by improving the percentage of bone formation and socket width (improved horizontal width and socket filling). In such patients, the healing index was higher and the VAS score for pain stimuli lower than in the control group.

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富含白细胞和血小板的纤维蛋白对拔牙效果的系统回顾和荟萃分析。

背景：拔牙是最常见的口腔手术，但拔牙会导致牙槽骨重塑，因此需要植入假牙进行修复。我们进行了荟萃分析，以确定富含白细胞和血小板的纤维蛋白（L-PRF）是否能改善拔牙效果：在对 Scopus、Web of science、ProQuest 和 PubMed 进行检索后，纳入了六项相关研究（239 名拔牙后使用 L-PRF 治疗的患者）：结果：L-PRF种植体患者拔牙后骨形成的百分比高于对照组，平均差异为-13.16（-15.89，-10.43）。L-PRF 种植体组的牙槽充填度和水平宽度也更高。一项分组荟萃分析显示，L-PRF 治疗组的愈合指数在拔牙后 7 天和 14 天明显更高。L-PRF组的疼痛刺激VAS评分低于对照组，平均差为1.26（1.00，1.51）；研究的异质性差异显著：这些结果表明，L-PRF 可通过改善骨形成比例和牙槽窝宽度（改善水平宽度和牙槽窝充填）来防止牙脊形成。与对照组相比，这类患者的愈合指数更高，疼痛刺激 VAS 评分更低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medicina Oral Patologia Oral Y Cirugia Bucal DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

4.60

自引率

0.00%

发文量

审稿时长

3-8 weeks

期刊介绍： 1. Oral Medicine and Pathology: Clinicopathological as well as medical or surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, as well as orofacial neurological disorders, and systemic conditions with an impact on the oral cavity. 2. Oral Surgery: Surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, teeth, implants, oral surgical procedures. Surgical management of diseases affecting head and neck areas. 3. Medically compromised patients in Dentistry: Articles discussing medical problems in Odontology will also be included, with a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients. 4. Implantology 5. Periodontology