Synchrotron CT dosimetry for wiggler operation at reduced magnetic field and spatial modulation with bow tie filters.

IF 2.5 3区 物理与天体物理
Journal of Synchrotron Radiation Pub Date : 2024-11-01 Epub Date: 2024-10-22 DOI:10.1107/S1600577524008531
Stewart Midgley, Nanette Schleich, Andrew Stevenson, Alex Merchant
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引用次数: 0

Abstract

The Australian Synchrotron Imaging and Medical Beamline (IMBL) uses a superconducting multipole wiggler (SCMPW) source, dual crystal Laue monochromator and 135 m propagation distance to enable imaging and computed tomography (CT) studies of large samples with mono-energetic radiation. This study aimed to quantify two methods for CT dose reduction: wiggler source operation at reduced magnetic field strength, and beam modulation with spatial filters placed upstream from the sample. Transmission measurements with copper were used to indirectly quantify the influence of third harmonic radiation. Operation at lower wiggler magnetic field strength reduces dose rates by an order of magnitude, and suppresses the influence of harmonic radiation, which is of significance near 30 keV. Beam shaping filters modulate the incident beam profile for near constant transmitted signal, and offer protection to radio-sensitive surface organs: the eye lens, thyroid and female breast. Their effect is to reduce the peripheral dose and the dose to the scanned volume by about 10% for biological samples of 35-50 mm diameter and by 20-30% for samples of up to 160 mm diameter. CT dosimetry results are presented as in-air measurements that are specific to the IMBL, and as ratios to in-air measurements that may be applied to other beamlines. As CT dose calculators for small animals are yet to be developed, results presented here and in a previous study may be used to estimate absorbed dose to organs near the surface and the isocentre.

利用弓形领带滤波器和空间调制进行同步加速器 CT 剂量测定。
澳大利亚同步加速器成像和医学光束线(IMBL)使用超导多极摆动(SCMPW)源、双晶 Laue 单色器和 135 米传播距离,利用单能量辐射对大型样品进行成像和计算机断层扫描(CT)研究。这项研究旨在量化两种减少 CT 剂量的方法:在磁场强度降低的情况下进行摆动源操作,以及使用放置在样品上游的空间滤波器进行光束调制。铜的透射测量用于间接量化三次谐波辐射的影响。在较低的触发器磁场强度下运行可将剂量率降低一个数量级,并抑制谐波辐射的影响,谐波辐射在 30 千伏附近具有重要影响。光束整形滤波器可调节入射光束轮廓,使传输信号接近恒定,并保护对辐射敏感的表面器官:眼球晶状体、甲状腺和女性乳房。其效果是,对于直径为 35-50 毫米的生物样本,可将外围剂量和扫描体积的剂量降低约 10%;对于直径达 160 毫米的样本,可将外围剂量和扫描体积的剂量降低 20-30%。CT 剂量测定结果以 IMBL 特有的空气中测量值和与空气中测量值的比率形式呈现,可用于其他光束线。由于用于小型动物的 CT 剂量计算器尚未开发出来,本文和之前一项研究的结果可用于估算表面和等中心附近器官的吸收剂量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Synchrotron Radiation
Journal of Synchrotron Radiation INSTRUMENTS & INSTRUMENTATIONOPTICS&-OPTICS
CiteScore
5.60
自引率
12.00%
发文量
289
审稿时长
1 months
期刊介绍: Synchrotron radiation research is rapidly expanding with many new sources of radiation being created globally. Synchrotron radiation plays a leading role in pure science and in emerging technologies. The Journal of Synchrotron Radiation provides comprehensive coverage of the entire field of synchrotron radiation and free-electron laser research including instrumentation, theory, computing and scientific applications in areas such as biology, nanoscience and materials science. Rapid publication ensures an up-to-date information resource for scientists and engineers in the field.
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