Esben Ahrens PhD , Poul Jennum DMSc , Jonas Duun-Henriksen PhD , Bjarki Djurhuus PhD , Preben Homøe DMSc , Troels W. Kjær PhD , Martin Christian Hemmsen PhD
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引用次数: 0
Abstract
Goal and aims
Performance evaluation of automatic sleep staging on two-channel subcutaneous electroencephalography.
Focus technology
UNEEG medical’s 24/7 electroencephalography SubQ (the SubQ device) with deep learning model U-SleepSQ.
Reference method/technology
Manually scored hypnograms from polysomnographic recordings.
Sample
Twenty-two healthy adults with 1-6 recordings per participant. The clinical study was registered at ClinicalTrials.gov with the identifier NCT04513743.
Design
Fine-tuning of U-Sleep in 11-fold cross-participant validation on 22 healthy adults. The resultant model was called U-SleepSQ.
Core analytics
Bland-Altman analysis of sleep parameters. Advanced multiclass model performance metrics: stage-specific accuracy, specificity, sensitivity, kappa (κ), and F1 score. Additionally, Cohen’s κ coefficient and macro F1 score. Longitudinal and participant-level performance evaluation.
Additional analytics and exploratory analyses
Exploration of model confidence quantification. Performance vs. age, sex, body mass index, SubQ implantation hemisphere, normalized entropy, transition index, and scores from the following three questionnaires: Morningness-Eveningness Questionnaire, World Health Organization’s 5-item Well-being Index, and Major Depression Inventory.
Core outcomes
There was a strong agreement between the focus and reference method/technology.
Important supplemental outcomes
The confidence score was a promising metric for estimating the reliability of each hypnogram classified by the system.
Core conclusion
The U-SleepSQ model classified hypnograms for healthy participants soon after implantation and longitudinally with a strong agreement with the gold standard of manually scored polysomnographics, exhibiting negligible temporal variation.
期刊介绍:
Sleep Health Journal of the National Sleep Foundation is a multidisciplinary journal that explores sleep''s role in population health and elucidates the social science perspective on sleep and health. Aligned with the National Sleep Foundation''s global authoritative, evidence-based voice for sleep health, the journal serves as the foremost publication for manuscripts that advance the sleep health of all members of society.The scope of the journal extends across diverse sleep-related fields, including anthropology, education, health services research, human development, international health, law, mental health, nursing, nutrition, psychology, public health, public policy, fatigue management, transportation, social work, and sociology. The journal welcomes original research articles, review articles, brief reports, special articles, letters to the editor, editorials, and commentaries.