Association between changes in depressive symptoms and risk of anemia: from the China Health and Retirement longitudinal study.

IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Yucong Bi, Liping Zheng, Leping Zhang, Longyang Han, Yang Liu, Xiaowei Zheng, Chongke Zhong
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Abstract

Background: Previous studies have reported that anemia was associated with depression, but the association between changes in depressive symptoms and the risk of anemia was unclear. This study aimed to explore whether changes in depressive symptoms were associated with anemia among the middle-aged and elderly adults.

Methods: A total of 6112 patients aged 45 years and older from the China Health and Retirement Longitudinal Study (CHARLS) were included in this analysis. Elevated Depression Symptoms (EDS) was defined as the Center for Epidemiological Studies Depression Scale-10 score ≥ 10. Depression status was defined as no depressive symptom [no EDS at Wave 1 (2011-2012) and Wave 2 (2013-2014)], decreasing depressive symptoms (EDS at Wave 1, no EDS at Wave 2), increasing depressive symptoms (no EDS at Wave 1, EDS at Wave 2), persistent depressive symptoms (EDS at Wave 1 and Wave 2). Multivariable logistic regression analyses were conducted to estimate the relationships between depressive symptoms and the changes and risk of anemia.

Results: During the follow-up of Wave 1 and Wave 3 (2015-2016), 906 participants (14.82%) developed anemia, the multivariable-adjusted odds ratio for the depressive symptom compared with the no depressive symptom was 1.24 (95% CI, 1.12-1.58) for anemia. From Wave 2 to Wave 3, there were 828 participants (14.62%) diagnosed with anemia. Compared to participants with no depressive symptom, those with persistent depressive symptoms during Wave 1 and Wave 2 had the significantly elevated risk of anemia (odds ratio 1.44, 95% CI 1.21-1.84).

Conclusions: The present study demonstrated that baseline depressive symptoms and changes in depressive symptoms were associated with increased risks of anemia.

抑郁症状变化与贫血风险之间的关系:来自中国健康与退休纵向研究。
背景:以前的研究曾报道贫血与抑郁有关,但抑郁症状的变化与贫血风险之间的关系尚不清楚。本研究旨在探讨抑郁症状的变化是否与中老年人贫血有关:本次分析共纳入了 6112 名中国健康与退休纵向研究(CHARLS)中 45 岁及以上的患者。流行病学研究中心抑郁量表-10评分≥10分为抑郁症状(EDS)升高。抑郁状态被定义为无抑郁症状[第1波(2011-2012年)和第2波(2013-2014年)无EDS]、抑郁症状减轻(第1波有EDS,第2波无EDS)、抑郁症状加重(第1波无EDS,第2波有EDS)、抑郁症状持续(第1波和第2波有EDS)。我们进行了多变量逻辑回归分析,以估计抑郁症状与贫血的变化和风险之间的关系:在第 1 波和第 3 波(2015-2016 年)的随访期间,906 名参与者(14.82%)出现了贫血,与无抑郁症状相比,抑郁症状导致贫血的多变量调整几率比为 1.24(95% CI,1.12-1.58)。从第二波到第三波,共有 828 名参与者(14.62%)被诊断为贫血。与没有抑郁症状的参与者相比,在第 1 波和第 2 波期间有持续抑郁症状的参与者患贫血的风险明显增加(几率比 1.44,95% CI 1.21-1.84):本研究表明,基线抑郁症状和抑郁症状的变化与贫血风险的增加有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Archives of Public Health
Archives of Public Health Medicine-Public Health, Environmental and Occupational Health
CiteScore
4.80
自引率
3.00%
发文量
244
审稿时长
16 weeks
期刊介绍: rchives of Public Health is a broad scope public health journal, dedicated to publishing all sound science in the field of public health. The journal aims to better the understanding of the health of populations. The journal contributes to public health knowledge, enhances the interaction between research, policy and practice and stimulates public health monitoring and indicator development. The journal considers submissions on health outcomes and their determinants, with clear statements about the public health and policy implications. Archives of Public Health welcomes methodological papers (e.g., on study design and bias), papers on health services research, health economics, community interventions, and epidemiological studies dealing with international comparisons, the determinants of inequality in health, and the environmental, behavioural, social, demographic and occupational correlates of health and diseases.
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