Rapid Healing of Palatal Necrosis with Active Oxygen Gel: A Case Report and Management Strategy.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Tatiana M Deliberador, Hassan Y Saleh, Eduardo Ferrucio, Jeferson Stroparo, Camila Pinheiro Furquim
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Abstract

BACKGROUND Managing unique anatomical structures, such as the nasopalatine canal, remains key for successful implant placement and long-term functionality. Topical oral oxygen therapy (TOOT) has gained attention for its antibacterial, regenerative properties, and ability to accelerate wound healing. This report presents a case of postoperative palatal necrosis successfully treated with TOOT oxygen-active gel (blue®m) CASE REPORT A 33-year-old male patient presented with the primary concern of needing rehabilitation of the anterior maxillary region. Clinical and imaging examinations revealed a deficient maxillary ridge and an enlarged incisive foramen. The treatment plan involved nasopalatine deflation with guided bone regeneration using particulate synthetic bone graft and a collagen membrane. Seven days after surgery, he returned with minimal pain but had necrotic tissue on the palate. The necrotic tissue and a portion of the contaminated biomaterial were removed, and the area was thoroughly cleansed with a saline solution. A thick layer of active oxygen gel (blue®m) was then applied to the palatal lesion. The patient was instructed to apply the gel 3 times daily for 30 days and attended follow-up appointments every 2 days. After 12 days, rapid healing and significant clinical improvement were observed, with the patient reporting no pain or sensitivity. By day 34, the lesion had fully closed, and re-epithelialization was achieved. CONCLUSIONS Our patient had complete resolution of palatal necrosis after nervus deflation using TOOT with active oxygen gel (blue®m), and this therapy seemed to accelerate the healing process.

用活性氧凝胶快速治愈腭部坏死:病例报告与治疗策略
背景 管理独特的解剖结构(如鼻腭管)仍然是成功植入种植体并实现长期功能的关键。局部口腔氧疗(TOOT)因其抗菌、再生特性和加速伤口愈合的能力而备受关注。本报告介绍了一例使用 TOOT 氧活性凝胶(blue®m)成功治疗术后腭部坏死的病例。 病例报告 一位 33 岁的男性患者前来就诊,主要考虑是需要进行上颌前牙区的康复治疗。临床和影像学检查显示其上颌嵴缺损,切迹孔增大。治疗方案包括鼻腭松解术,以及使用颗粒合成骨移植和胶原膜引导骨再生。术后七天,他的疼痛减轻,但上腭有坏死组织。坏死组织和部分被污染的生物材料被移除,并用生理盐水彻底清洗了该区域。然后在腭部病变部位涂上一层厚厚的活性氧凝胶(blue®m)。医生嘱咐患者每天涂抹 3 次凝胶,持续 30 天,并每两天复诊一次。12 天后,观察到病灶迅速愈合,临床症状明显改善,患者表示没有疼痛或敏感症状。到第 34 天,病灶完全闭合,实现了再上皮化。结论 我们的患者在使用含活性氧凝胶(blue®m)的 TOOT 软化神经后,腭部坏死完全愈合,而且这种疗法似乎加快了愈合过程。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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