{"title":"[Call attention to the role of chronic endometritis in recurrent pregnancy loss].","authors":"Y H Yang, W Y Huang","doi":"10.3760/cma.j.cn112137-20240416-00896","DOIUrl":null,"url":null,"abstract":"<p><p>Chronic endometritis (CE) refers to the persistent inflammation of endometrium and is closely associated with infertility. Recurrent pregnancy loss (RPL), which has complex etiological factors, is two or more pregnancy loss of a couple before 20 weeks. However, CE is found in approximately 30% RPL patients, indicating that the endometrial immune microenvironment disorder caused by CE may play important role in RPL. Therefore, we should pay high attention and give CE screening to the RPL patients. Due to the inconsistent diagnostic criteria of CE, the relationship between RPL and CE remains controversial. Antibiotic is the primary treatment of CE. Using the higher CE diagnosis value can ensure effective treatment to RPL patient, and avoid the abuse of antibiotic. The effective treatment of CE can improve the pregnant outcomes of RPL patient.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"104 39","pages":"3642-3646"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zhonghua yi xue za zhi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/cma.j.cn112137-20240416-00896","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Chronic endometritis (CE) refers to the persistent inflammation of endometrium and is closely associated with infertility. Recurrent pregnancy loss (RPL), which has complex etiological factors, is two or more pregnancy loss of a couple before 20 weeks. However, CE is found in approximately 30% RPL patients, indicating that the endometrial immune microenvironment disorder caused by CE may play important role in RPL. Therefore, we should pay high attention and give CE screening to the RPL patients. Due to the inconsistent diagnostic criteria of CE, the relationship between RPL and CE remains controversial. Antibiotic is the primary treatment of CE. Using the higher CE diagnosis value can ensure effective treatment to RPL patient, and avoid the abuse of antibiotic. The effective treatment of CE can improve the pregnant outcomes of RPL patient.
慢性子宫内膜炎(CE)是指子宫内膜的持续性炎症,与不孕症密切相关。复发性妊娠失败(RPL)的病因复杂,是指一对夫妇在 20 周前两次或两次以上妊娠失败。然而,约 30% 的 RPL 患者存在 CE,这表明 CE 导致的子宫内膜免疫微环境紊乱可能在 RPL 中扮演重要角色。因此,我们应高度重视并对 RPL 患者进行 CE 筛查。由于 CE 的诊断标准不统一,RPL 与 CE 的关系仍存在争议。抗生素是治疗 CE 的主要方法。使用较高的 CE 诊断值可以确保 RPL 患者得到有效治疗,避免抗生素的滥用。有效治疗 CE 可以改善 RPL 患者的妊娠结局。