Clinico-epidemiological profiling of dengue patients in a non-endemic region of Bangladesh.

IF 1.9 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-03 DOI:10.1093/trstmh/trae074

Md Mohiuddin Khan, Md Abdul Hannan Miah, Mohammad Khurshed Alam, Mohammad Ariful Islam, Md Atikur Rahman, Ramim Islam Ibne Noor, Ershad Mondal, A H M Shalakin Mamun, Md Rasel, Md Rubaiyat Tasfin Talukder, Salwa Islam, Mohammad Jahid Hasan

{"title":"Clinico-epidemiological profiling of dengue patients in a non-endemic region of Bangladesh.","authors":"Md Mohiuddin Khan, Md Abdul Hannan Miah, Mohammad Khurshed Alam, Mohammad Ariful Islam, Md Atikur Rahman, Ramim Islam Ibne Noor, Ershad Mondal, A H M Shalakin Mamun, Md Rasel, Md Rubaiyat Tasfin Talukder, Salwa Islam, Mohammad Jahid Hasan","doi":"10.1093/trstmh/trae074","DOIUrl":null,"url":null,"abstract":"Background: This study aimed to characterise the clinical and epidemiological profiles of dengue patients and their outcomes during an ongoing outbreak in a non-endemic region of Bangladesh.Methods: This prospective observational study analysed 805 confirmed dengue cases during August-December 2023. Data on demographic, clinical and laboratory profiles, as well as outcomes, were gathered using a structured questionnaire. Statistical analysis was conducted using SPSS 25.Results: The mean age of dengue patients was 31.5 (±12.2) y, with the majority being males (81.2%). All 805 patients experienced fever, 792 (98.4%) had headaches, 698 (86.7%) had myalgia, 601 (74.7%) had persistent vomiting and 598 (74.3%) had abdominal pain. Bleeding was observed in 191 (23.7%) patients and neurological symptoms were seen in 209 (25.9%) patients. Most patients (n=781, 97%) exhibited non-severe symptoms, while 3% (n=24) had severe symptoms. Among the 24 severe cases, four (16.7%) patients were reported to have encephalitis and one (4.2%) patient had meningoencephalitis. Moreover, 365 patients (45.3%) had travelled to an endemic region who were predominantly males (n=327, 89.6%). Most dengue patients recovered well with rapid fluid replacement therapy (n=754, 93.7%).Conclusions: The 2023 dengue outbreak in a non-endemic area of Bangladesh primarily impacted males, young adults, with the majority presenting non-severe symptoms. Further studies are essential to validate and build upon these results.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":"58-64"},"PeriodicalIF":1.9000,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transactions of The Royal Society of Tropical Medicine and Hygiene","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/trstmh/trae074","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}

引用次数: 0

Abstract

Background: This study aimed to characterise the clinical and epidemiological profiles of dengue patients and their outcomes during an ongoing outbreak in a non-endemic region of Bangladesh.

Methods: This prospective observational study analysed 805 confirmed dengue cases during August-December 2023. Data on demographic, clinical and laboratory profiles, as well as outcomes, were gathered using a structured questionnaire. Statistical analysis was conducted using SPSS 25.

Results: The mean age of dengue patients was 31.5 (±12.2) y, with the majority being males (81.2%). All 805 patients experienced fever, 792 (98.4%) had headaches, 698 (86.7%) had myalgia, 601 (74.7%) had persistent vomiting and 598 (74.3%) had abdominal pain. Bleeding was observed in 191 (23.7%) patients and neurological symptoms were seen in 209 (25.9%) patients. Most patients (n=781, 97%) exhibited non-severe symptoms, while 3% (n=24) had severe symptoms. Among the 24 severe cases, four (16.7%) patients were reported to have encephalitis and one (4.2%) patient had meningoencephalitis. Moreover, 365 patients (45.3%) had travelled to an endemic region who were predominantly males (n=327, 89.6%). Most dengue patients recovered well with rapid fluid replacement therapy (n=754, 93.7%).

Conclusions: The 2023 dengue outbreak in a non-endemic area of Bangladesh primarily impacted males, young adults, with the majority presenting non-severe symptoms. Further studies are essential to validate and build upon these results.

查看原文本刊更多论文

孟加拉国非流行地区登革热病人的临床流行病学概况。

背景：本研究旨在了解孟加拉国非疫区登革热疫情爆发期间登革热患者的临床和流行病学特征及其结果：本研究旨在描述孟加拉国非流行地区登革热疫情爆发期间登革热病人的临床和流行病学特征及其结果：这项前瞻性观察研究分析了 2023 年 8 月至 12 月期间的 805 例登革热确诊病例。通过结构化问卷收集了有关人口统计学、临床和实验室概况以及结果的数据。统计分析采用 SPSS 25：登革热患者的平均年龄为 31.5 (±12.2) 岁，男性占多数（81.2%）。所有 805 名患者均发烧，792 人（98.4%）头痛，698 人（86.7%）肌痛，601 人（74.7%）持续呕吐，598 人（74.3%）腹痛。191名（23.7%）患者出现出血，209名（25.9%）患者出现神经症状。大多数患者（781 人，97%）症状不严重，3%（24 人）症状严重。在 24 例严重病例中，有 4 例（16.7%）患者患有脑炎，1 例（4.2%）患者患有脑膜脑炎。此外，365 名患者（45.3%）曾前往登革热流行地区，其中男性居多（327 人，89.6%）。大多数登革热患者在接受快速液体补充治疗后恢复良好（754人，占93.7%）：2023年在孟加拉国非流行区爆发的登革热疫情主要影响男性和青壮年，大多数患者症状并不严重。进一步的研究对于验证和巩固这些结果至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Transactions of The Royal Society of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.00

自引率

9.10%

发文量

115

审稿时长

4-8 weeks

期刊介绍： Transactions of the Royal Society of Tropical Medicine and Hygiene publishes authoritative and impactful original, peer-reviewed articles and reviews on all aspects of tropical medicine.