{"title":"Risk factors associated with respiratory distress syndrome in late preterm infants.","authors":"Hongbin Zhu, Yueyi Wang, Haiwei Yin, Fang Liu, Yanfei Ma, Xinyue Li","doi":"10.12669/pjms.40.9.9078","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To investigate the risk factors for neonatal respiratory distress syndrome (NRDS) in late preterm infants.</p><p><strong>Method: </strong>A retrospective analysis was performed on the clinical data of 86 late preterm infants with a gestational age of 34-36<sup>+6</sup> weeks who were admitted to Maternity & Child Care Center of Qinhuangdao from June 2022 to June 2023 and with complete clinical records. All enrolled infants were divided into the non-NRDS group(<i>n</i>=51) and the NRDS group(<i>n</i>=35) according to the presence or absence of NRDS.</p><p><strong>Result: </strong>No statistically significant differences were observed in birth weight, gestational age and gravidity between the two groups(<i>p></i>0.05), while there were statistically significant differences in fetal gender, mode of delivery and presence or absence of asphyxia(<i>p<</i>0.05). Moreover, no statistically significant differences were found in advanced maternal age, anemia, multiple births, and gestational hypertension(<i>p></i>0.05), while there were statistically significant differences in placental abnormalities, intrauterine distress, premature rupture of membranes, and gestational diabetes mellitus(<i>p<</i>0.05). Logistic regression analysis revealed that fetal gender(male), placental abnormalities, intrauterine distress, premature rupture of membranes, and gestational diabetes mellitus were risk factors for NRDS in late preterm infants(<i>p<</i>0.05).</p><p><strong>Conclusion: </strong>Late preterm infants suffer from NRDS due to a variety of complex pathogenic causes, with numerous complications. Factors such as male fetal gender, placental abnormalities, intrauterine distress, premature rupture of membranes, and gestational diabetes mellitus may increase the risk of NRDS in late preterm infants. In clinical observation, it is necessary to strengthen monitoring efforts and take timely measures to intervene in the course of NRDS.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"40 9","pages":"1947-1952"},"PeriodicalIF":1.2000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11476139/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan Journal of Medical Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12669/pjms.40.9.9078","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To investigate the risk factors for neonatal respiratory distress syndrome (NRDS) in late preterm infants.
Method: A retrospective analysis was performed on the clinical data of 86 late preterm infants with a gestational age of 34-36+6 weeks who were admitted to Maternity & Child Care Center of Qinhuangdao from June 2022 to June 2023 and with complete clinical records. All enrolled infants were divided into the non-NRDS group(n=51) and the NRDS group(n=35) according to the presence or absence of NRDS.
Result: No statistically significant differences were observed in birth weight, gestational age and gravidity between the two groups(p>0.05), while there were statistically significant differences in fetal gender, mode of delivery and presence or absence of asphyxia(p<0.05). Moreover, no statistically significant differences were found in advanced maternal age, anemia, multiple births, and gestational hypertension(p>0.05), while there were statistically significant differences in placental abnormalities, intrauterine distress, premature rupture of membranes, and gestational diabetes mellitus(p<0.05). Logistic regression analysis revealed that fetal gender(male), placental abnormalities, intrauterine distress, premature rupture of membranes, and gestational diabetes mellitus were risk factors for NRDS in late preterm infants(p<0.05).
Conclusion: Late preterm infants suffer from NRDS due to a variety of complex pathogenic causes, with numerous complications. Factors such as male fetal gender, placental abnormalities, intrauterine distress, premature rupture of membranes, and gestational diabetes mellitus may increase the risk of NRDS in late preterm infants. In clinical observation, it is necessary to strengthen monitoring efforts and take timely measures to intervene in the course of NRDS.
期刊介绍:
It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad.
Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.