Challenges and applications in generative AI for clinical tabular data in physiology.

IF 2.9 4区 医学 Q2 PHYSIOLOGY
Chaithra Umesh, Manjunath Mahendra, Saptarshi Bej, Olaf Wolkenhauer, Markus Wolfien
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引用次数: 0

Abstract

Recent advancements in generative approaches in AI have opened up the prospect of synthetic tabular clinical data generation. From filling in missing values in real-world data, these approaches have now advanced to creating complex multi-tables. This review explores the development of techniques capable of synthesizing patient data and modeling multiple tables. We highlight the challenges and opportunities of these methods for analyzing patient data in physiology. Additionally, it discusses the challenges and potential of these approaches in improving clinical research, personalized medicine, and healthcare policy. The integration of these generative models into physiological settings may represent both a theoretical advancement and a practical tool that has the potential to improve mechanistic understanding and patient care. By providing a reliable source of synthetic data, these models can also help mitigate privacy concerns and facilitate large-scale data sharing.

生理学临床表格数据生成式人工智能的挑战与应用。
人工智能生成方法的最新进展开辟了合成表格临床数据生成的前景。从填补真实世界数据中的缺失值,这些方法现已发展到创建复杂的多表格。本综述探讨了能够合成患者数据和多表建模的技术的发展。我们强调了这些方法在生理学患者数据分析中面临的挑战和机遇。此外,它还讨论了这些方法在改进临床研究、个性化医疗和医疗保健政策方面的挑战和潜力。将这些生成模型整合到生理学环境中,既是理论上的进步,也是有可能提高机理理解和患者护理的实用工具。通过提供可靠的合成数据源,这些模型还有助于减轻对隐私的担忧,促进大规模数据共享。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
8.80
自引率
2.20%
发文量
121
审稿时长
4-8 weeks
期刊介绍: Pflügers Archiv European Journal of Physiology publishes those results of original research that are seen as advancing the physiological sciences, especially those providing mechanistic insights into physiological functions at the molecular and cellular level, and clearly conveying a physiological message. Submissions are encouraged that deal with the evaluation of molecular and cellular mechanisms of disease, ideally resulting in translational research. Purely descriptive papers covering applied physiology or clinical papers will be excluded. Papers on methodological topics will be considered if they contribute to the development of novel tools for further investigation of (patho)physiological mechanisms.
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