Prognostic Significance of Early Posttreatment Audiometry in Idiopathic Sudden Sensorineural Hearing Loss.

IF 2.6 3区医学 Q1 OTORHINOLARYNGOLOGY

Otolaryngology- Head and Neck Surgery Pub Date : 2025-02-01 Epub Date: 2024-10-13 DOI:10.1002/ohn.1009

Harel Sofer, Ran Fisher, Yehuda Tarnovsky, Gaelle Vofo, Michal Kaufmann, Sagit Stern Shavit

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引用次数: 0

Abstract

Objective: This study aimed to assess the prognostic value of early posttreatment initiation audiometry findings in patients with idiopathic sudden sensorineural hearing loss (ISSHL).

Study design: A retrospective cohort study.

Setting: The study was conducted at a single tertiary medical center.

Methods: A review was conducted on 299 ISSHL patients treated between 2007 and 2023. Patients underwent audiometry on Days 2 to 3 and 5 to 7 posttreatment initiation. Data on demographics, medical history, audiometry results, and prognosis were collected. Prognosis was categorized based on hearing recovery at 1 year postdiagnosis.

Results: Older age, worse initial speech reception threshold (SRT), ischemic heart disease, cerebrovascular accidents/transient ischemic attacks, hypertension, and diabetes were associated with a poorer prognosis. Posttreatment initiation audiometry findings on Days 2 to 3 and 5 to 7 significantly correlated with prognosis. Patients with a ≥30% improvement had substantial or complete recovery in over 80% of cases, while those with <10% had <30% recovery. Multivariate analysis identified a significant improvement on days 5 to 7 as an independent predictor of complete recovery (odds ratio = 4.25 [95% confidence interval 1.96-9.23], P = .0002).

Conclusion: Posttreatment initiation audiometry findings, particularly on Days 5 to 7, hold significant prognostic value in ISSHL patients. A substantial improvement during this timeframe is strongly associated with favorable outcomes. These findings emphasize the potential of posttreatment initiation audiometry as a valuable tool for clinicians in counseling patients with ISSHL.

查看原文本刊更多论文

特发性突发性感音神经性听力损失患者治疗后早期测听的预后意义。

研究目的本研究旨在评估特发性突发性感音神经性听力损失（ISSHL）患者治疗后早期听力测定结果的预后价值：研究设计：回顾性队列研究：环境：研究在一家三级医疗中心进行：方法：对 2007 年至 2023 年间接受治疗的 299 名 ISSHL 患者进行回顾性研究。患者在治疗开始后的第 2 至 3 天和第 5 至 7 天接受了听力测定。收集了有关人口统计学、病史、测听结果和预后的数据。根据诊断后 1 年的听力恢复情况对预后进行分类：结果：年龄较大、初始言语接收阈值（SRT）较低、患有缺血性心脏病、脑血管意外/短暂性脑缺血发作、高血压和糖尿病的患者预后较差。治疗后第 2 至 3 天和第 5 至 7 天的听力测定结果与预后密切相关。听力改善≥30%的患者中，超过80%的患者已基本康复或完全康复，而听力改善≥30%的患者中，超过80%的患者已基本康复或完全康复：治疗开始后的测听结果，尤其是第 5 至 7 天的测听结果，对 ISSHL 患者的预后具有重要价值。在这段时间内听力大幅改善与良好的预后密切相关。这些发现强调了开始治疗后测听仪作为临床医生咨询 ISSHL 患者的重要工具的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Otolaryngology- Head and Neck Surgery 医学-耳鼻喉科学

CiteScore

6.70

自引率

2.90%

发文量

250

审稿时长

2-4 weeks

期刊介绍： Otolaryngology–Head and Neck Surgery (OTO-HNS) is the official peer-reviewed publication of the American Academy of Otolaryngology–Head and Neck Surgery Foundation. The mission of Otolaryngology–Head and Neck Surgery is to publish contemporary, ethical, clinically relevant information in otolaryngology, head and neck surgery (ear, nose, throat, head, and neck disorders) that can be used by otolaryngologists, clinicians, scientists, and specialists to improve patient care and public health.