{"title":"Improving equivalent scores for clinical neuropsychology: a new method for regression model selection.","authors":"Giorgio Arcara","doi":"10.1007/s10072-024-07806-z","DOIUrl":null,"url":null,"abstract":"<p><p>Equivalent Scores (ES) represent a statistical gold standard to obtain thresholds for clinical inference from normative data. The procedure to obtain ES requires a preliminary mandatory step: to perform a regression model selection to obtain adjusted scores that take into account age, education, and sex. The current article, starting from theoretical considerations, focuses on this step and proposes a new and improved regression model selection method. Results from data simulation show that the newly proposed method outperforms the current one on a wide range of simulation parameters and conditions, leading to better performance in classifying impaired or unimpaired performances, and more precise ES. The article is associated with an online app and R code to allow to easily apply the method to other normative data. This new model selection procedure can be easily incorporated also with other regression-based norm approaches.</p>","PeriodicalId":19191,"journal":{"name":"Neurological Sciences","volume":" ","pages":"5685-5695"},"PeriodicalIF":2.7000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurological Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10072-024-07806-z","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/17 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Equivalent Scores (ES) represent a statistical gold standard to obtain thresholds for clinical inference from normative data. The procedure to obtain ES requires a preliminary mandatory step: to perform a regression model selection to obtain adjusted scores that take into account age, education, and sex. The current article, starting from theoretical considerations, focuses on this step and proposes a new and improved regression model selection method. Results from data simulation show that the newly proposed method outperforms the current one on a wide range of simulation parameters and conditions, leading to better performance in classifying impaired or unimpaired performances, and more precise ES. The article is associated with an online app and R code to allow to easily apply the method to other normative data. This new model selection procedure can be easily incorporated also with other regression-based norm approaches.
等效分(ES)代表了从常模数据中获得临床推断阈值的统计黄金标准。获得 ES 的程序需要一个初步的强制性步骤:进行回归模型选择,以获得考虑年龄、教育程度和性别的调整分数。本文从理论出发,重点讨论了这一步骤,并提出了一种新的改进型回归模型选择方法。数据模拟结果表明,在各种模拟参数和条件下,新提出的方法都优于现有方法,从而能更好地对受损或未受损表现进行分类,并使 ES 更精确。文章附有在线应用程序和 R 代码,可轻松将该方法应用于其他标准数据。这种新的模型选择程序也可以很容易地与其他基于回归的常模方法相结合。
期刊介绍:
Neurological Sciences is intended to provide a medium for the communication of results and ideas in the field of neuroscience. The journal welcomes contributions in both the basic and clinical aspects of the neurosciences. The official language of the journal is English. Reports are published in the form of original articles, short communications, editorials, reviews and letters to the editor. Original articles present the results of experimental or clinical studies in the neurosciences, while short communications are succinct reports permitting the rapid publication of novel results. Original contributions may be submitted for the special sections History of Neurology, Health Care and Neurological Digressions - a forum for cultural topics related to the neurosciences. The journal also publishes correspondence book reviews, meeting reports and announcements.