Natalia Moreno, Florencia C Lynch, María A Zalazar, Carla F Miranda, Sofía H Vidal, Marisa L Armeno
{"title":"[Decreased vision due to hypovitaminosis A in children with food selectivity].","authors":"Natalia Moreno, Florencia C Lynch, María A Zalazar, Carla F Miranda, Sofía H Vidal, Marisa L Armeno","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Vitamin A deficiency can cause eye disease and has been related to food selectivity in children with autism spectrum disorder (ASD).</p><p><strong>Methods: </strong>A series of 13 pediatric patients with severe ophthalmological involvement as an initial manifestation of hypovitaminosis A is described.</p><p><strong>Results: </strong>With significant Vitamin A deficiency, neuroimaging was performed in 11 patients. Of these, 8 had pathological findings with the presence of cranial hyperostosis. Lumbar puncture was performed in these patients and endocranial hypertension was detected in 7 of the 8 patients. All had food selectivity and 61.5% had ASD.</p><p><strong>Conclusions: </strong>Toxic-nutritional optic neuropathy is a rare pathology in children and presents with progressive, bilateral and painless visual loss due to damage to the optic nerve, which can generate severe and irreversible damage to it. Food history allows early detection of nutrient deficiencies in children with restrictive feeding, especially in neuro-atypical patients. This is essential to implement preventive measures and treatment with vitamin A in order to avoid irreversible consequences.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 5","pages":"860-867"},"PeriodicalIF":0.6000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina-buenos Aires","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Vitamin A deficiency can cause eye disease and has been related to food selectivity in children with autism spectrum disorder (ASD).
Methods: A series of 13 pediatric patients with severe ophthalmological involvement as an initial manifestation of hypovitaminosis A is described.
Results: With significant Vitamin A deficiency, neuroimaging was performed in 11 patients. Of these, 8 had pathological findings with the presence of cranial hyperostosis. Lumbar puncture was performed in these patients and endocranial hypertension was detected in 7 of the 8 patients. All had food selectivity and 61.5% had ASD.
Conclusions: Toxic-nutritional optic neuropathy is a rare pathology in children and presents with progressive, bilateral and painless visual loss due to damage to the optic nerve, which can generate severe and irreversible damage to it. Food history allows early detection of nutrient deficiencies in children with restrictive feeding, especially in neuro-atypical patients. This is essential to implement preventive measures and treatment with vitamin A in order to avoid irreversible consequences.
简介:维生素 A 缺乏可导致眼疾,并与自闭症谱系障碍(ASD)儿童的食物选择性有关:维生素A缺乏可导致眼部疾病,并与自闭症谱系障碍(ASD)儿童的食物选择性有关:方法:本文描述了13例以严重眼病作为维生素A缺乏症初期表现的儿童患者:结果:由于维生素 A 严重缺乏,11 名患者接受了神经影像学检查。结果:对 11 名严重缺乏维生素 A 的患者进行了神经影像学检查,其中 8 人的病理结果显示存在颅骨骨质增生。对这些患者进行了腰椎穿刺,在 8 名患者中有 7 名发现了颅内高压。所有患者都有食物选择性,61.5%患有自闭症:中毒性营养性视神经病变是一种罕见的儿童病症,表现为由于视神经受损导致的进行性、双侧和无痛性视力丧失,可对视神经造成严重和不可逆的损伤。通过食物史可以及早发现限制性喂养儿童的营养缺乏情况,尤其是神经异常患者。这对于采取预防措施和维生素 A 治疗以避免不可逆转的后果至关重要。