[Acquired hemophilia - quick diagnosis and treatment can significantly reduce the risk of mortality].

Lakartidningen Pub Date : 2024-10-09
Jolene Johansson, Mårten Söderberg
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引用次数: 0

Abstract

This case report of a 73-year-old male with bleedings provides insights into the clinical characteristics, diagnosis och treatment of acquired hemophilia A. It's a dangerous non-hereditary bleeding disorder caused by autoantibodies against coagulation factor VIII, often linked with other autoimmune diseases or malignancies, but it is also often idiopathic. The diagnosis remains a challenge due to its rarity and non-specific symtoms, but should be considered in unexplained bleeding cases with prolonged activated partial thromboplastin time (APTT). Quick  diagnosis and treatment can significantly reduce the risk of serious complications and mortality. The long-term prognosis usually depends on the presence of any underlying disease.

[获得性血友病--快速诊断和治疗可大大降低死亡风险]。
这是一种危险的非遗传性出血性疾病,由针对凝血因子 VIII 的自身抗体引起,通常与其他自身免疫性疾病或恶性肿瘤有关,但也常常是特发性的。由于其罕见性和非特异性症状,该病的诊断仍是一个难题,但对于活化部分凝血活酶时间(APTT)延长的不明原因出血病例,应予以考虑。快速诊断和治疗可大大降低严重并发症和死亡的风险。长期预后通常取决于是否存在任何潜在疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Lakartidningen
Lakartidningen Medicine-Medicine (all)
CiteScore
0.30
自引率
0.00%
发文量
134
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