Related Factors of Syphilis Positive Rate in Blood Donors During the COVID-19 Epidemic.

IF 2.1 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

International Journal of General Medicine Pub Date : 2024-10-09 eCollection Date: 2024-01-01 DOI:10.2147/IJGM.S481519

Song-Xing Wang, Li-Yan Sun, Qiong Yu, Ran Li, Yun-Ping Xu, Jin-Feng Zeng

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引用次数: 0

Abstract

Background: In Shenzhen of China, the continuous increase of syphilis infections threatens the safety of blood transfusion. In 2020, COVID-19 was discovered and spread rapidly around the world, and affected the prevalence of syphilis among blood donors.

Methods: From 2013 to 2020, there were 839,161 blood samples collected in the Shenzhen Blood Center. Blood samples were screened by ELISA tests and confirmed by the TPPA (Treponema pallidum particle agglutination) tests and the TRUST (toluidine red unheated serum tests). All data was analyzed by the chi-square test.

Results: From 2013 to 2020, the positive rate of syphilis among blood donors varied significantly among individuals in different ages, educational backgrounds, regions, and blood donation histories (P<0.001). In 2020, It was the first time that there were more repeat blood donors than first-time blood donors and more blood donors with a higher education level than those with a lower education level, and the lowest reactive and positive rate of syphilis among blood donors was observed. Compared to 2019, the prevalence of syphilis among female and repeat blood donors decreased significantly in 2020 (P<0.01).

Conclusion: The prevalence of syphilis in blood donors is related to the characteristics of blood donors (in addition to gender) and the COVID-19 epidemic. COVID-19 can affect the prevalence of syphilis among blood donors by influencing the composition of blood donors and the number of syphile-positive donors in certain blood donors, including female and repeat blood donors.

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COVID-19 流行期间献血者梅毒阳性率的相关因素。

背景：在中国深圳，梅毒感染率的持续上升威胁着输血安全。2020年，COVID-19被发现并在全球迅速传播，影响了献血者梅毒感染率：方法：2013 年至 2020 年，深圳市血液中心共采集血样 839 161 份。方法：从2013年至2020年，深圳市中心血站共采集839 161份血样，通过ELISA检测进行筛查，并通过TPPA（苍白螺旋体颗粒凝集试验）和TRUST（甲苯胺红未加热血清试验）进行确诊。所有数据均通过卡方检验进行分析：结果：从2013年到2020年，不同年龄、教育背景、地区和献血史的献血者梅毒阳性率有显著差异（PPC结论：献血者梅毒阳性率在不同年龄、教育背景、地区和献血史的献血者中存在显著差异：梅毒在献血者中的流行与献血者的特征（除性别外）和 COVID-19 的流行有关。COVID-19 可通过影响献血者的组成以及某些献血者（包括女性献血者和重复献血者）中梅毒阳性献血者的数量来影响献血者中的梅毒感染率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of General Medicine Medicine-General Medicine

自引率

0.00%

发文量

1113

审稿时长

16 weeks

期刊介绍： The International Journal of General Medicine is an international, peer-reviewed, open access journal that focuses on general and internal medicine, pathogenesis, epidemiology, diagnosis, monitoring and treatment protocols. The journal is characterized by the rapid reporting of reviews, original research and clinical studies across all disease areas. A key focus of the journal is the elucidation of disease processes and management protocols resulting in improved outcomes for the patient. Patient perspectives such as satisfaction, quality of life, health literacy and communication and their role in developing new healthcare programs and optimizing clinical outcomes are major areas of interest for the journal. As of 1st April 2019, the International Journal of General Medicine will no longer consider meta-analyses for publication.