Unveiling connections: bisphenol A and vitamin D dynamics in breast milk among healthy lactating mothers.

IF 2.2 4区医学 Q3 ENVIRONMENTAL SCIENCES

International Journal of Environmental Health Research Pub Date : 2024-10-10 DOI:10.1080/09603123.2024.2412118

Esra Cinkilli Aktağ, Sıddika Songül Yalçin, Anıl Yіrün, Aylin Balci Özyurt, Pınar Erkekoğlu

{"title":"Unveiling connections: bisphenol A and vitamin D dynamics in breast milk among healthy lactating mothers.","authors":"Esra Cinkilli Aktağ, Sıddika Songül Yalçin, Anıl Yіrün, Aylin Balci Özyurt, Pınar Erkekoğlu","doi":"10.1080/09603123.2024.2412118","DOIUrl":null,"url":null,"abstract":"<p><p>Bisphenol A (BPA) has negative impact on human health. This study aims to explore the association between the levels of BPA and 25(OH) vitamin D in breastmilk. BPA exposure and vitamin D sources were recorded on the study form. Breastmilk 25(OH) vitamin D was measured by the competitive enzyme-linked immunosorbent assay method, and BPA was analyzed by fluorescence detector high pressure liquid chromatography technique. Multiple logistic regression analysis were performed for association. Among 70 lactating mothers, the median 25(OH) vitamin D level was 12.6 ng/mL. In 92.9% of breastmilk samples, detectable levels of BPA were found, with a median BPA concentration of 2.56 ng/mL. However, both univariate and multivariate analyses failed to reveal any association between breastmilk BPA and 25(OH) vitamin D levels. This lack of association in healthy lactating mothers, highlighting the need for further research to comprehensively understand the intricate dynamics of these factors.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-13"},"PeriodicalIF":2.2000,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Environmental Health Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09603123.2024.2412118","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Bisphenol A (BPA) has negative impact on human health. This study aims to explore the association between the levels of BPA and 25(OH) vitamin D in breastmilk. BPA exposure and vitamin D sources were recorded on the study form. Breastmilk 25(OH) vitamin D was measured by the competitive enzyme-linked immunosorbent assay method, and BPA was analyzed by fluorescence detector high pressure liquid chromatography technique. Multiple logistic regression analysis were performed for association. Among 70 lactating mothers, the median 25(OH) vitamin D level was 12.6 ng/mL. In 92.9% of breastmilk samples, detectable levels of BPA were found, with a median BPA concentration of 2.56 ng/mL. However, both univariate and multivariate analyses failed to reveal any association between breastmilk BPA and 25(OH) vitamin D levels. This lack of association in healthy lactating mothers, highlighting the need for further research to comprehensively understand the intricate dynamics of these factors.

查看原文本刊更多论文

揭开联系的面纱：健康哺乳母亲母乳中双酚 A 和维生素 D 的动态变化。

双酚 A（BPA）对人体健康有负面影响。本研究旨在探讨母乳中双酚 A 水平与 25(OH) 维生素 D 之间的关联。研究表中记录了双酚 A 暴露和维生素 D 来源。母乳中 25(OH) 维生素 D 的含量采用竞争性酶联免疫吸附法测定，双酚 A 的含量采用荧光检测器高压液相色谱法分析。对两者的相关性进行了多元逻辑回归分析。在 70 位哺乳母亲中，25（OH）维生素 D 水平的中位数为 12.6 纳克/毫升。在 92.9% 的母乳样本中发现了可检测到的双酚 A 水平，双酚 A 浓度中位数为 2.56 纳克/毫升。然而，单变量和多变量分析均未发现母乳中的双酚 A 与 25(OH) 维生素 D 水平之间存在任何关联。在健康的哺乳期母亲中缺乏这种关联，这突出表明需要进一步研究，以全面了解这些因素的复杂动态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of Environmental Health Research 医学-公共卫生、环境卫生与职业卫生

CiteScore

6.70

自引率

3.10%

发文量

134

审稿时长

>12 weeks

期刊介绍： International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.