Veno-arterial extracorporeal membrane oxygenation supported transcatheter aortic valve implantation in a high-risk COVID-19 patient: a comprehensive case report.

Pub Date : 2024-09-26 eCollection Date: 2024-09-01 DOI:10.1093/ehjcr/ytae457
Giampiero Vizzari, Tommaso De Ferrari, Francesco Costa, Nastasia Mancini, Marco Franzino, Fabrizio Ceresa, Francesco Patanè, Antonio Micari
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Abstract

Background: The sudden onset of heart failure in high-risk transcatheter aortic valve implantation (TAVI) candidates poses significant challenges, necessitating meticulous planning and consideration of mechanical circulatory support options. Nevertheless, existing data on the efficacy and safety of mechanical circulatory support in this context are limited, along with criteria for patient selection.

Case summary: An 87-year-old patient, with severe low-flow low-gradient aortic stenosis, presented with acute heart failure and concurrent COVID-19 pneumonia. Despite initial conservative management, her clinical condition deteriorated, requiring inotropic support. The decision was made to perform a rescue TAVI procedure with veno-arterial extracorporeal membrane oxygenation (ECMO) support. The patient underwent successful TAVI while managing complications, including cardiac arrest, with haemodynamic support from veno-arterial ECMO. Post-procedure, the patient showed improved cardiac function and was discharged in stable condition.

Discussion: This case underscores the significance of strategic patient selection, proactive haemodynamic management, and the judicious use of veno-arterial ECMO in high-risk TAVI, particularly in complex scenarios involving acute heart failure and respiratory insufficiency, exacerbated by COVID-19. It highlights the challenges and critical decision points in TAVI planning, emphasizing the need for further research and standardized guidelines to refine indications for prophylactic mechanical circulatory support in TAVI procedures.

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一名高风险 COVID-19 患者的静脉-动脉体外膜氧合支持经导管主动脉瓣植入术:一份综合病例报告。
背景:高风险经导管主动脉瓣植入术(TAVI)候选者突然出现心力衰竭是一项重大挑战,需要精心策划和考虑机械循环支持方案。然而,有关机械循环支持在这种情况下的疗效和安全性的现有数据以及患者选择标准都很有限。病例摘要:一位 87 岁的患者患有严重的低流量低梯度主动脉瓣狭窄,出现急性心衰并并发 COVID-19 肺炎。尽管最初采取了保守治疗,但她的临床状况恶化,需要肌力支持。最终决定在静脉-动脉体外膜肺氧合(ECMO)支持下进行抢救性 TAVI 手术。在静脉-动脉 ECMO 的血流动力学支持下,患者成功进行了 TAVI 手术,同时控制了包括心脏骤停在内的并发症。术后,患者心功能得到改善,病情稳定出院:本病例强调了在高风险 TAVI 中战略性选择患者、积极主动的血流动力学管理和慎重使用静脉-动脉 ECMO 的重要性,尤其是在涉及急性心衰和呼吸功能不全的复杂情况下,COVID-19 会加重病情。报告强调了 TAVI 计划中的挑战和关键决策点,强调了进一步研究和标准化指南的必要性,以完善 TAVI 手术中预防性机械循环支持的适应症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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